Thank you Steff and Wayne and bless you both! I know that there have been a few patients in my Dr.'s care that responded to the Opdivo but the side effects were either to much to take or the Opdivo attacked their internal organs so they were forced to consider other options. I try to keep my hopes set on remission but i also have to sort all of my life into boxes for my kids and husband, this depresses me, so i quit but i know i have to do it. Sometimes it's hard to stay positive when you are preparing for your own death.All of our family live in Il. and we live in Ga. we moved here almost 7 years ago because my husbands place of employment moved here, so no friends here either and the hubs don't know what to say and to be honest he would rather not talk about my cancer. Now don't get me wrong he loves me and goes to every infusion and Dr. appointment which is every other week, he just don't want to talk about my possible death and i don't know if i am weird but my death does not scare me but i am worried about my husband and kids and dog and cat lol