Alisa

Thank you for posting this, Lauren ... I just found it by accident when I googled my name for something else

Hi Shirley, It is absolutely normal to get scared, angry and tired of it at times. No one can be positive all the time and one of my pet peeves is "oh attitude is everything", etc. etc. It is not. Obviously the better the attitude the better the days are but we have to real and acknowledge all our feelings. And no one should feel guilty or bad or anything when they have down phases. Most people don't know what to say to us and sometimes ask questions or say something that may not feel good to us, all part of this journey. Sending you well wishes ..... Alisa 15 year Survivor NSCLC

Hi Teri, I didn't have my whole lung removed but I know of 3 people who did and they are all doing fine now. I'm going to share your post on my FB page and share it privately with my friend who had her whole lung removed. Hopefully she will give you some input. The fact that the doctors feel surgery applies is a good thing! Warmly, Alisa

Hello everyone! It has been years since I've posted, but I have been keeping up with the Facebook Message Boards. I am wondering if anyone knows anything at all about this blood test for lung cancer. Does anyone know any hospitals in the US working with the Early CDT test? I couldn't find any in my online search. Thanks! http://www.earlycdt-lung.co.uk/patient

Hi guys, it's been a long time since I've been on the message board. I've been connecting mainly through LUNGevity and Hope Summit Facebook page, but wanted to share this interesting article with you all. From previous board messages, I know many of us are taking PSP/PSK Corliolus Versicolor Mushroom as adjuvant therapy for lung cancer. This article is about a dog who was treated successfully for cancer with PSP. I've been on PSP since my diagnosis 14 years ago. I was going to put in under the Alternative Treatment thread, but it's not really alternative (and one should let their doctor know what they are taking) and I see that thread hasn't been active for almost a year, so I posted here. Hope it's okay http://ivanhoe.com/channels/p_channelst ... ryid=32835

Hey Janet, I am so sorry to hear how badly you've been feeling. But I'm more sorry to hear you feel like you are failing or quitting. Your body knows when you need a rest. It takes a fighter to know that too. Can you take a little break to get some strength back and then start up again? Is that the plan?

I'm so sorry to hear about Geri. <^>

Judy, I get it!!!! I wish I could write down my feelings like you do, but that would mean I'd have to deal with them Thank you for posting this.

I've been taking good quality proanthocyanidins for years .... UAB finds grape extract that kills lung cancer cells By Paul Hamaker, Birmingham Science News Examiner ..Researchers at the University of Alabama at Birmingham and the Birmingham Veterans Affairs Medical Center announced the discovery of the effective use of grape seed proanthocyanidins to produce cancer cell death in lung cancer at the Public Library of Science web site on November 8, 2011. "If, the body weight of a normal standard person is considered to be 70 Kg, then 1.13 g GSPs will be required for a healthy person/day to produce same level of anti-lung carcinogenic effects as observed in mice, which seems reasonable, affordable and attainable. In summary, the novelty of this study lies in the analysis of chemotherapeutic effects of GSPs on additional new molecular targets of NSCLC cells using both in vitro and in vivo models. This detailed and systematic study revealed that GSPs induce apoptosis of human non-small cell lung cancer cells by loss of mitochondrial membrane potential, which was not reported earlier in this model. The present findings provide pre-clinical data suggesting that grape seed proanthocyanidins have the potential to be developed as a pharmacologically safe agent either alone or in combination with other drugs for the treatment of non-small cell lung cancers in humans." Lung cancer remains the leading cause of cancer-related deaths worldwide, and non-small cell lung cancer (NSCLC) represents approximately 80% of total lung cancer cases. The use of non-toxic dietary phytochemicals can be considered as a chemotherapeutic strategy for the management of the NSCLC. Here, we report that grape seed proanthocyanidins (GSPs) induce apoptosis of NSCLC cells, A549 and H1299, in vitro which is mediated through increased expression of pro-apoptotic protein Bax, decreased expression of anti-apoptotic proteins Bcl2 and Bcl-xl, disruption of mitochondrial membrane potential, and activation of caspases 9, 3 and poly (ADP-ribose) polymerase (PARP). Pre-treatment of A549 and H1299 cells with the caspase-3 inhibitor (z-DEVD-fmk) significantly blocked the GSPs-induced apoptosis of these cells confirmed that GSPs-induced apoptosis is mediated through activation of caspases-3. Treatments of A549 and H1299 cells with GSPs resulted in an increase in G1 arrest. G0/G1 phase of the cell cycle is known to be controlled by cyclin dependent kinases (Cdk), cyclin-dependent kinase inhibitors (Cdki) and cyclins. Our western blot analyses showed that GSPs-induced G1 cell cycle arrest was mediated through the increased expression of Cdki proteins (Cip1/p21 and Kip1/p27), and a simultaneous decrease in the levels of Cdk2, Cdk4, Cdk6 and cyclins. Further, administration of 50, 100 or 200 mg GSPs/kg body weight of mice by oral gavage (5 d/week) markedly inhibited the growth of s.c. A549 and H1299 lung tumor xenografts in athymic nude mice, which was associated with the induction of apoptotic cell death, increased expression of Bax, reduced expression of anti-apoptotic proteins and activation of caspase-3 in tumor xenograft cells. Based on the data obtained in animal study, human equivalent dose of GSPs was calculated, which seems affordable and attainable. Together, these results suggest that GSPs may represent a potential therapeutic agent for the non-small cell lung cancer. Paper Grape Proanthocyanidins Induce Apoptosis by Loss of Mitochondrial Membrane Potential of Human Non-Small Cell Lung Cancer Cells In Vitro and In Vivo Authors Tripti Singh2, Som D. Sharma2, Santosh K. Katiyar1,2,3,4* 1 Birmingham Veterans Affairs Medical Center, Birmingham, Alabama, United States of America, 2 Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, 3 Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, 4 Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America Citation: Singh T, Sharma SD, Katiyar SK (2011) Grape Proanthocyanidins Induce Apoptosis by Loss of Mitochondrial Membrane Potential of Human Non-Small Cell Lung Cancer Cells In Vitro and In Vivo. PLoS ONE 6(11): e27444. doi:10.1371/journal.pone.0027444 .Suggested by the author:Lung cancer vaccine prevents cancer progressionUAB finds green tea component that reduces skin cancer spread. 2 SharePrintEmail Continue reading on Examiner.com UAB finds grape extract that kills lung cancer cells - Birmingham science news | Examiner.com http://www.examiner.com/science-news-in ... z1fgmUVJvu

Great news! Thanks for posting

If you email me your at alisa.brenes@gmail.com and send me your email address, I can send you my list and where I get them from ...

Thank you all!!!!! Everyone on the board is an inspiration

Thank you all so much for the well wishes. It is overwhelming how caring you all are. I also feel blessed to have this community! Love, Alisa

Hello cyber family, I haven't been on the boards for a while, between time constraints and recent losses, it's been hard for me to get here. But I just went for my scan - I usually get scanned every 6 months even though the doctor recommended a yearly schedule now, but after 8 months I couldn't take the anxiety of waiting, so I went - and I wanted to share my good news to give others hope. It's been 11 years since surgery and my last chemo treatment and I am still NED (No Evidence of Disease for any newbies) !!!!! I thank God every day for this blessing.

http://www.sciencedaily.com/releases/20 ... 111656.htm Vitamin D Linked to Lung Cancer Survival, Study Suggests ScienceDaily (Mar. 1, 2011) — Recent research suggests vitamin D may be able to stop or prevent cancer. Now, a new study finds an enzyme that plays a role in metabolizing vitamin D can predict lung cancer survival.