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Showing content with the highest reputation since 06/24/2019 in Posts

  1. 4 points
    Rower Michelle

    Durvalumab

    I’m willing to sell tickets to that show down tomorrow! Anyway, I’m looking at the June 2019 American Society of Oncology Association. (ASCO) abstracts. It appears as if your medical team is humming along with the new chemo immunotherapy protocol. Typically administered when there is no PDL-1 or targeted mutation. Early studies suggest good results in PFS. Ask the doc to show you which abstract is most applicable and have them provide you with a copy. Sounds like this is going to be worth it in the long run. Good luck-lock and load.
  2. 3 points
    Kleo

    Durvalumab

    Yes Rower Michelle!.... This is the new protocol now....just as the durva was. Gotta wonder..... how similar are Tecentriq and durvalumab considering they target the same thing? Just like Keytruda and durvalumab….🤔
  3. 2 points
    Robert Macaulay

    Durvalumab

    Kleo If this makes sense please let me know😎 Atezolizumab (Tecentriq®) Atezolizumab (Tecentriq, Genentech USA, Inc, San Francisco, CA, USA) is a monoclonal antibody that binds to PD-L1 and blocks its interaction with PD-1, thereby enhancing T-cell activity against tumor cells.21 Durvalumab (Imfinzi®) Durvalumab (Imfinzi, AstraZeneca, Cambridge, UK) is a human IgG1κ monoclonal antibody that blocks the interaction of PD-L1 with the PD-1 and CD80 (B7.1) molecules.25
  4. 2 points
    Kleo

    Durvalumab

    Tecentriq is alot like Durva...targets PDL1. I don't have any PDL1 expression. Why am I taking a medicine that targets something I don't even have!?? Seems silly to me. I said that to my onc last time and she said sometimes it works even without PDL1. So does Durva apparently….that's why they give it to everyone regardless! But it didn't work on me... I don't know I just feel like the PDL1 immunos are not my thing. I guess we will battle it out tomorrow...LOL JaneLee….my onc told me the bad shoulder pain I got during durva was probably bursitis..? couldn't lift my arm at all. Then it went completely away after I stopped the durva. That's just ME though...I'm pretty weird! 😏
  5. 2 points
    Donna, the potential for major tissue damage with leakage of chemo drugs into the tissues is the very reason I asked for a port. Also, for the six days in a row that I will receive chemo, if I didn’t have a port, I understand I would have a new IV started each day. That’s nuts!!! So the potential to blow six veins would exist and who knows what. Wow you got this combo 22 years ago??? I guess that’s good to know, if you are communicating with me on this board in 2019!!! So happy you are still cancer free and really happy you replied to my post. You have given me much hope. Blessings to you. adding: So very sorry you lost your husband to lung cancer.
  6. 2 points
    Robert Macaulay

    Durvalumab

    Kleo Don't feel like this is the right stuff for me. I bet he will convince you otherwise. 😎
  7. 2 points
    Kleo

    Durvalumab

    Haahaaahaaa! Bob you are so funny!🤣 Yeah they just approved that Tecentriq/ Avastin combo with chemo here. So that's what they are trying...even though I don't have PDL1😣 I'm gonna have a lil chat with my onc Wed. Don't feel like this is the right stuff for me.
  8. 2 points
    Kleo

    Durvalumab

    I think they are just tossing the dang alphabet at me! Here try this new Gerfloogerbaghin...it'll help.
  9. 1 point
    Roz

    Clinical Trial update

    Thanks everyone! I've been told that sometimes there is progression at the 6 week scan and that the immunotherapy combo doesn't kick in until the 12 week scan. I'm still crossing all my fingers and toes too for Thursday's scan. It would be nice to have some proof that it's working. Take care!! Best, Ro
  10. 1 point
    Tom Galli

    Clinical Trial update

    Ro, I’ve got my fingers and toes crossed for a good news consult. Stay the course. Tom
  11. 1 point
    Rower Michelle

    Clinical Trial update

    You got it! Harvard is working on developing an ALK vaccine but it’s not ready for prime time. Whatever they learn in your trial will likely benefit all of us. I’m so grateful you’ve got the gravitas to pull through this! Hang in there!
  12. 1 point
    Roz

    Clinical Trial update

    Hi Michelle, I would say that I mainly feel okay. There's a fever for about a day, stomach aches and fatigue. But with treatment on Tuesday, I find that I feel better by Thursday. I'm usually back at the gym by Friday...The trial is time intensive and I'm really eager to see what the scan shows. They say that you may not see results at the 6 weeks scan, and they advice you to continue with the protocol through the 12 week scan..so that's exactly what I'll do.. Thanks for your support!! Ro
  13. 1 point
    Rower Michelle

    Clinical Trial update

    Hi Ro I hope this goes well for you. It’s a really interesting trial- gives me such great hope!! Are you feeling okay? You rock! Michelle
  14. 1 point
    Roz

    Just diagnosed

    Hi SandyK, I was diagnosed one month before I turned age 60 and my situation was like your wife's in that I maintained a healthy lifestyle, worked out regularly, have no family history of this, etc. My diagnosis was Stage IV NSCLC Mucionus Adenocarcinoma.(KRAS mutation)- I had my lower left lung lobe removed using VATS in Sept 2017 and then my upper Right lung lobe removed with an open thoracotomy in October 2017. This was followed by chemo. There was a brief period of NED, and then there was evidence of recurrence in the lower right lobe. I have been taking part in a Phase Ib Clinical trial that uses a personal cancer vaccine and an immunotherapy drug (Tecentriq)..there are lots of options available and I agree what others have said, "knowledge is power." Try to education yourselves as much as possible so that you know what questions to ask. I'm happy to answer any questions once you know more of the specifics regarding typed of cancer. One step at a time, and remember you have this entire network of supporters on this forum ready to help and/or make suggestions. Best, Ro
  15. 1 point
    Curt

    Just diagnosed

    I was diagnosed a few months ago. I went through a year of scans following a lung nodule that was discovered by accident when I got an abdominal scan for something else. I was lucky to be able to have surgery as a treatment and haven’t required any follow up treatment. Just semi annual scans. I have the unfortunate experience of having had family members with lung cancer diagnosis. Five of my fathers nine siblings have been diagnosed, my father included. That was a while back and the treatments available today were not available to him. I’m glad they exist now but it hurts to know that just a few years could have made such a big difference on his prognosis. Stage IV lung cancer is still a tough disease to fight but it’s not as insurmountable as it was when he was diagnosed.
  16. 1 point
    Tomm

    Durvalumab

    Hi Kelo, You really have an attitude of such a fighter and taking everything they toss at you and believing in your future. Positive forward thinking is a good thing for all of us. I am really sorry to hear your dealing with pain and I hope your team helps. I hope you have great success with your new protocol. Rower.. That's some nice research you did reading the Society of Oncology Association. (ASCO) abstracts. I'll try and read that too. Possible Durvalumab people: I want you to know that not everyone gets bad side effects but some that do are nice enough to share that information with us so we know what can happen and what to monitor. I am getting infusion #6 on Thursday, my thyroid is off THS 29.63 and I have fatigue and that's all. I have a Naturopath Oncologist that has me taking 18 natural supplements & coconut water. Other Durvalumab Patients: Please post that you are doing well or not and share that good and the bad, it will help others to know we are not alone. good luck fellow travelers
  17. 1 point
    Curt

    Just diagnosed

    I’m sorry to hear about your wife’s diagnosis SandyK. You’ve gotten some great guidance and advice from Michelle and Tom. Ignore the numbers on the internet (they are dated), educate yourself and definitely get good genetic testing done. Not all panels are created equal. Targeted therapies for specific types of lung cancer can be more affective. Sometimes this disease requires one hour at a time. Your wife is lucky to have such a great support system. Hang in there.
  18. 1 point
    Charles

    Durvalumab

    Hey Kleo I'd try a hit of that Gerflooberglobbin over here but I'm still pixellating on the Prednisone, it sounds a little German to me though, somethin like Der Gooberflobbin is akickin se poopinhockin outen mein poopinhopper, but in all honesty and seriousness am sorry to hear about the pain with the new treatments, seems if it aint one tham dang it's another right?
  19. 1 point
    Barb1260

    Durvalumab

    Grouchy is acceptable. Sorry about the pain. I’ve only had 4 infusions and I have pain in my foot joints occasionally which I had for years then it went away during chemo and radiation. Never figured that out
  20. 1 point
    Robert Macaulay

    Durvalumab

    Kleo What you are receiving was just approved in Canada three weeks ago. Gerfloogerbaghin sounds Scottish
  21. 1 point
    BridgetO

    Hiccups

    Hi Debby. I use an acupressure point to stop hiccups and have found it more effective than others I've tried. It's also supposed to help with nausea and vomiting but I can't vouch for that. I didn't know about it when I had chemo years ago for a prior non-lung cancer. Here's a video from Sloan Kettering that shows the point. Let me know if it works for him https://www.mskcc.org/cancer-care/patient-education/acupressure-nausea-and-vomiting
  22. 1 point
    Debby eastwood

    Hiccups

    Hi Everyone After my first post a month ago we found out my Husband has Nsclc. He received 5 days of radiotherapy that significantly reduced the pain to his shoulder with very little side effects. Last week ( 2 weeks later) Chemo started for the first time. He’s having immunotherapy, pemetrexed and carboplatin. He keeps getting hiccups anyone else had this and any remedies to reduce although not bothering him that much just very annoying. It’s day 3 after treatment and apart from feeling fatigued all is ok. Debby
  23. 1 point
    Sandyk

    Just diagnosed

    Tom thanks for the info. every little bit really does help. I"m checking into weather or not they ordered a full panel or not. I'll also see about the exact type of Non small cell LC she has. One day at a time I guess.
  24. 0 points
    Kleo

    Durvalumab

    This is off topic but I just gotta say it......this chemo/immuno cocktail is BLEHK!😣 Anyway...when I was on the durva...my biggest problem/side effect I saw was that it caused me joint and muscle pains in my back and arms. Sent me to the ER twice they were so bad. So now they are giving me this...Tecentriq stuff...and I'm having joint/muscle pains again..but all over. Even my legs! So how do I know if it's the immuno again or the taxol or whatever else they've tossed in my salad!? Too many thingies! I'm grouchy today....sorry 😉
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