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wendyh

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Everything posted by wendyh

  1. Thank you KatieB. I will follow up on these leads. My mother is starting a phase 3 study today! We are hopeful, but I know we've got to figure out this KRAS issue. My assumption is that immunotherapy is going to be the answer.
  2. Liz - I'm so sorry and know how hard it is. The comment above about targeted therapies - that's what path we're on now too- dealing with NSCLC (my mother), Stage IV, inoperable. However, I'm also now learning that things change - cancer is far trickier than I ever realized, and you have to constantly research, evaluate and look for new approaches. My mother is now entering a Phase 3 study - so much is happening in research - and that is reason to be hopeful too. Happy to share more if that helps. I new to this board, so wanted to reach out and say hi as well. Wendy
  3. My mother was diagnosed about 2 years ago with Stage IIIb / IV NSCLC (one site w/pleural effusion). The tumor is inoperable due to location (and no radiation option either). She tested positive for the EGFR mutation and has been on Tarceva (after chemo - Alimta, Carboplatin, Avastin) for just over one year. Now the cancer is growing, and they tested for the T790 mutation, likely to be present once resistance to Tarceva shows. However, not only did they find the EGFR and T790 mutations, but they now see the KRAS mutation, which is highly unusual. The KRAS and EGFR are considered to be mutually exclusive. I'm interested to know if anyone has encountered this? We're getting her into a study for the T790, but not certain about options to address the KRAS mutation.
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