Opal

Kleo, or shall I say Dr Kleo, you are too funny but you were right on, it seems about flu shot and infusion too much at the same time. Sending prayers and all good thoughts for you on your needle biopsy. You won't feel a thing! Eagle13, wonderful to hear about your CT results and targeted therapy!!

Bob, thanks for reply. I did have both within hours and then rash started. After some searching I found there have been few studies on flu "jab" and Immuno in Basel Switzerland and Kleo was right!! The combination together did have big effect on my system.

Bob, Kleo, wonder if either of you got the flu shot while on Durvalumab

Bob, it took a minute but I get it! Thanks for that!! Eagle 13, after reading your reply I do recall reading that thru this journey. Thanks for the link. And for your story.

Eagle13, I agree and also don't understand why this isn't done first. I'm going to inquire next appointment. May I ask what is difference in targeted therapy and immunotherapy you were getting? Good luck next week on CT. Maybe you will share. "Never underestimate the power of prayer"

Kleo, I was taking Prednisone 70mg daily. Fairly high dose. I was fine on them. Except made me cranky, eat eat and eat more, and cry for no reason. Oh and sleep was limited. I've heard some people had worse side effects so probably everyone reacts differently. TRIPLETS lol! Then maybe I wouldn't get any side effects either😀 (from durva). Keep us posted on rad doc visit. Sending prayers. Bob, Re the link on antibiotics, OK now I'm wondering about those antibiotics I took while my Immuno was on hold. So even tho it was only on Mon, Wed, Fri while I was on steroids. Wonder if that cancelled out 3 prior infusions. Shall I sing Que sera sera???😥 Next visit I'm asking about Biomarkers. I didn't have done either.

I got fingers crossed you won't need Prednisone and have to stop Durva. I begged they take me off the Prednisone. Wish I was on West coast but on East coast.

Bob, I had inflammation too. I believe that's why they kept me on steroids longer and added the antibiotics.

Hey Kleo, you are passing me by number on infusions now. I would have been on schedule with you and Bob if I didn't have to stop for a month. I go Wednesdays or Thursday whenever I can get an appointment or "chair". I'm pretty sure pneumonitis would show up on CT or PET. I was put on antibiotics along with the Prednisone, they were being cautious, in case whatever showed on my CT scan was pneumonitis. Turns out it wasn't. Glad your spasms stopped. I didn't get any Durva basket either😞 so don't feel alone on that one.

Kleo, I did resume the Durva on Nov 28. Going again on 12/ I too, wondered why you were getting PET and not CT. Think positive! Hey your tumor shrunk and that's great news. Bob, can you clarify what you wrote in your post an hour ago about the flu shot? I got my flu shot on the same day as infusion #3! Yikes! BTW I've been coughing too. Seems worse in the evening. I too am taking cough med. I'm happy so far 1 week since infusion and only an itch here and there YIKES! same nurse gave me flu shot THEN did my infusion. May be the reason I got the travelling "rash"!? I think I am posting the whole message again. Not figured out how this work. Anyway you have been OK with Immuno so any reaction I'd think could be antibiotic. Good luck and thanks for your experience and pointers with this.😊

Kleo, I did resume the Durva on Nov 28. Going again on 12/13. I too, wondered why you were getting PET and not CT. Think positive! Hey your tumor shrunk and that's great news. Bob, can you clarify what you wrote in your post an hour ago about the flu shot? I got my flu shot on the same day as infusion #3! Yikes! BTW I've been coughing too. Seems worse in the evening. I too am taking cough med. I'm happy so far 1 week since infusion and only an itch here and there.

It seems to be a common side effect yet not much out there about it.

Thanks for sharing. I'll see if I can find it here. I'm using RX steriod creams costing a fortune and not stopping the rash. My rash doesn't itch, just looks ugly. I can live with it but wish I knew if it really was the immunotherapy causing it. Thanks again for info. I hope I can get back on and do as well as you are!!

Hey Bob, would you mind sharing what the itch cream is? Maybe it is the answer to my rash. As I'm still scratching here haha. Actually seems my rash is easing up so not sure if from tapered steroids or almost 2 months since last infusion.

I haven't seen anything more posted on Durvalumab. Wondering if I'm not looking in right place on site, or are those on this immunotherapy doing well with it and no side effects? Would love to hear from you. I had 3 infusions and my oncologist put me on hold until my rash clears up. Seems next start date for me is end of Nov with hopes rash doesn't return.

Got my fingers crossed for you too. Thanks for your reply.

Hi! I'm newbie here and finding way around site. Wondering if anyone on Durvalumab got the "rash" or other side effects? I started #1 infusion of Durv 8/30, then 9/11 and 9/27 and few days after 8/30 I started getting bumpy skin which turned into red bumps and is still moving to new areas. Doc stopped 10/9 immune and put me on 70 mg Prednisone. I'm tapering down now. Still have red bumps. Altho not a crazy itch it isn't pretty. I'm due for CT for radiation doc 11/1. Scanexiety! From what I see on site seems I'm close to a couple others doing this same immuno. I'd love to hear from you.