Salem

My dad got his results back and there is no mutation detected. He has pdl1 which is the good thing. Does anyone know if no mutation has any impact on reoccurrence after curative treatment? Is there any positive what so every to having no mutation. This is for stage 3 adenocarcinoma.

My dad will be doing Cisplatin for 1 day and Etoposide for 5 days on week 1, Cisplatin for 1 day on week 2, break on week 3 and repeat for cycle for week 4 and 5 along side radiation. I noticed most people with sclc on this forum get treated with these drugs and am interested if anyone with nsclc got chemo with these drugs.

Hi @Tom Galli, Definitely unusual considering he has been getting ct scans for empheyma twice a year for the last 10 years. Thought that if this was ever happened it would be found earlier but lymph nodes were normal on the scan in august so I assume it’s aggressive. Thank you for all the information it is a huge aid in understanding what we are dealing with. best, salem

Hi @Tom Galli Thank you for the explanation I couldn’t have asked for any more. We have come to terms with the diagnosis and the doctor said he is hopeful as they are going for a curative treatment of chemo radiation for 6 weeks. When you say metastatic does that apply to stage 3b as well? The doctor told us it is 3b after this PET scan was done. I noticed some people use metastatic to describe stage 3 but mostly stage 4 on the forum.

My dad got back the pet scan result and was diagnosed with 3b adenocarcinoma. Can someone help me understand what this is saying? Is having an SUV this hig bad? FINDINGS: No FDG avid cervical soft tissue mass or lymph nodes are present. FDG avid mediastinal adenopathy is demonstrated. Right paratracheal deposit measuring up to 2.9 cm has an SUV max of 18.6 Pretracheal and prevascular deposits measuring up to 2.5 cm with an SUV max of 20.1 are present. FDG avid subcarinal deposit measuring approximately 4.4 cm with an SUV max of 17.8 is demonstrated. No FDG avid hilar lymph nodes are present. No FDG avid supraclavicular, axillary, internal mammary or cardiophrenic lymph nodes are present. A small pericardial effusion is present. No pleural effusion is present. No FDG avid pulmonary nodule or mass is demonstrated. Physiologic uptake is demonstrated within the abdominopelvic organs. No FDG avid abdominopelvic adenopathy is present. No FDG avid body wall lesion is present. No worrisome FDG avid osseous lesion is demonstrated. IMPRESSION: The previously described mediastinal adenopathy has progressed. The lymph nodes are intensely FDG avid typical of malignant tissue. No definite FDG avid pulmonary mass is present. The mass within the paraesophageal/paratracheal location may be pulmonary/pleural in origin or represent enlarging lymph node. No FDG avid tissue is present outside of the thorax.

@Kelvin4426 dm’d you

@Kelvin4426 my dad is 62 and is starting 3b treatment in a few weeks or so. They said they are doing chemo radiation to cure it. I am also from Vancouver and my dad is getting treated at bc cancer agency on 10th.

@Justin1970 Hi Justin, Thanks for the response. Reading all the survival stories has gotten our spirits up for sure. Wish you the best of luck with treatment.

@Judy M2 Thank you for sharing your journey. At this point we are gonna hope for the best and that his bio markers are promising and there is no brain Mets and we will go from there. I see the 5 year survival is a coin toss with recent improvements almost but we are hoping for the best. Once a patient passes the 5 year survival rate does it look better for 10 years or does it not make a different? Also are there any cases of people staying NED. I am still quite young which is why I am more concerned about my father’s longevity.

Still waiting on the genes to come back to know more but this is what they confirmed thus far. What is the outlook for this type of cancer? They could not find a nodule in the lungs but found adenocarcinoma associated with lc in 2 lymph nodes. I thought this would be associated with a better prognosis but since it’s in the lymph system apparently it doesn’t make a difference. Was told it’s not curable at stage 3 but am wondering if it is possible to maintain it and for how long is the maximum before I can go to stage 4 or is it guaranteed to get there eventually? Microscopic Description Immunohistochemical stains were performed on block A2 with adequate controls for CK AB1/AE3 , CD45. CD3. CD20, CK7, CK20, TTF-1. Napsin-A, p40, S100, CDX2 GATA3. PAX& and synaptophysin. The tumor cells are positive for CK AE1/AE3, CK7, TTF-1, and Napsin-A. The tumor cells are negative for all other markers Cytologic evaluation shows large discohesive tumor cells that are positive for CK AE1 / 3, CK7, with variable positivity for TTF-1 and focal positivity for Napsin-A. The tumor cells are negative for p40 and synaptophysin. All other markers tested are negative. These findings favour diagnosis of metastatic non-small cell adenocarcinoma of lung primary origin. Clinical and radiographic correlation are recommended.