Hello...I am reading your story. Your wife and you are troopers!
My husband also has EGFR exon 19 del and was diagnosed with stage 1b lung cancer back in 2021. This past January 2023, he ended up in ER with seizure to later find out that he had Stage IV Brain Mets from his NSCLC. They resected one brain tumor, however about 11 remain. He has had 15 days WBRT and has been on Tagrisso since Mid February. He has adenocarcinoma type. Might I ask the dosage of Tagrisso your wife is on? My husband is at 120mg, however doctor wishes for him to get to the max dose of 160mg for full brain penetration. He just can't handle the increase just yet. He is very fatigued and I don't know if it is from the Tagrisso, the radiation, or the cancer.
I will check out the trial you mentioned. I have read many of the FLAURA articles and research. Some help but some do not.
Hang in there Ace!