Alisa

Thank you for posting this, Lauren ... I just found it by accident when I googled my name for something else

Hi Shirley, It is absolutely normal to get scared, angry and tired of it at times. No one can be positive all the time and one of my pet peeves is "oh attitude is everything", etc. etc. It is not. Obviously the better the attitude the better the days are but we have to real and acknowledge all our feelings. And no one should feel guilty or bad or anything when they have down phases. Most people don't know what to say to us and sometimes ask questions or say something that may not feel good to us, all part of this journey. Sending you well wishes ..... Alisa 15 year Survivor NSCLC

Hi Teri, I didn't have my whole lung removed but I know of 3 people who did and they are all doing fine now. I'm going to share your post on my FB page and share it privately with my friend who had her whole lung removed. Hopefully she will give you some input. The fact that the doctors feel surgery applies is a good thing! Warmly, Alisa

Hello everyone! It has been years since I've posted, but I have been keeping up with the Facebook Message Boards. I am wondering if anyone knows anything at all about this blood test for lung cancer. Does anyone know any hospitals in the US working with the Early CDT test? I couldn't find any in my online search. Thanks! http://www.earlycdt-lung.co.uk/patient

Hi guys, it's been a long time since I've been on the message board. I've been connecting mainly through LUNGevity and Hope Summit Facebook page, but wanted to share this interesting article with you all. From previous board messages, I know many of us are taking PSP/PSK Corliolus Versicolor Mushroom as adjuvant therapy for lung cancer. This article is about a dog who was treated successfully for cancer with PSP. I've been on PSP since my diagnosis 14 years ago. I was going to put in under the Alternative Treatment thread, but it's not really alternative (and one should let their doctor know what they are taking) and I see that thread hasn't been active for almost a year, so I posted here. Hope it's okay http://ivanhoe.com/channels/p_channelst ... ryid=32835

Hey Janet, I am so sorry to hear how badly you've been feeling. But I'm more sorry to hear you feel like you are failing or quitting. Your body knows when you need a rest. It takes a fighter to know that too. Can you take a little break to get some strength back and then start up again? Is that the plan?

I'm so sorry to hear about Geri. <^>

Judy, I get it!!!! I wish I could write down my feelings like you do, but that would mean I'd have to deal with them Thank you for posting this.

I've been taking good quality proanthocyanidins for years .... UAB finds grape extract that kills lung cancer cells By Paul Hamaker, Birmingham Science News Examiner ..Researchers at the University of Alabama at Birmingham and the Birmingham Veterans Affairs Medical Center announced the discovery of the effective use of grape seed proanthocyanidins to produce cancer cell death in lung cancer at the Public Library of Science web site on November 8, 2011. "If, the body weight of a normal standard person is considered to be 70 Kg, then 1.13 g GSPs will be required for a healthy person/day to produce same level of anti-lung carcinogenic effects as observed in mice, which seems reasonable, affordable and attainable. In summary, the novelty of this study lies in the analysis of chemotherapeutic effects of GSPs on additional new molecular targets of NSCLC cells using both in vitro and in vivo models. This detailed and systematic study revealed that GSPs induce apoptosis of human non-small cell lung cancer cells by loss of mitochondrial membrane potential, which was not reported earlier in this model. The present findings provide pre-clinical data suggesting that grape seed proanthocyanidins have the potential to be developed as a pharmacologically safe agent either alone or in combination with other drugs for the treatment of non-small cell lung cancers in humans." Lung cancer remains the leading cause of cancer-related deaths worldwide, and non-small cell lung cancer (NSCLC) represents approximately 80% of total lung cancer cases. The use of non-toxic dietary phytochemicals can be considered as a chemotherapeutic strategy for the management of the NSCLC. Here, we report that grape seed proanthocyanidins (GSPs) induce apoptosis of NSCLC cells, A549 and H1299, in vitro which is mediated through increased expression of pro-apoptotic protein Bax, decreased expression of anti-apoptotic proteins Bcl2 and Bcl-xl, disruption of mitochondrial membrane potential, and activation of caspases 9, 3 and poly (ADP-ribose) polymerase (PARP). Pre-treatment of A549 and H1299 cells with the caspase-3 inhibitor (z-DEVD-fmk) significantly blocked the GSPs-induced apoptosis of these cells confirmed that GSPs-induced apoptosis is mediated through activation of caspases-3. Treatments of A549 and H1299 cells with GSPs resulted in an increase in G1 arrest. G0/G1 phase of the cell cycle is known to be controlled by cyclin dependent kinases (Cdk), cyclin-dependent kinase inhibitors (Cdki) and cyclins. Our western blot analyses showed that GSPs-induced G1 cell cycle arrest was mediated through the increased expression of Cdki proteins (Cip1/p21 and Kip1/p27), and a simultaneous decrease in the levels of Cdk2, Cdk4, Cdk6 and cyclins. Further, administration of 50, 100 or 200 mg GSPs/kg body weight of mice by oral gavage (5 d/week) markedly inhibited the growth of s.c. A549 and H1299 lung tumor xenografts in athymic nude mice, which was associated with the induction of apoptotic cell death, increased expression of Bax, reduced expression of anti-apoptotic proteins and activation of caspase-3 in tumor xenograft cells. Based on the data obtained in animal study, human equivalent dose of GSPs was calculated, which seems affordable and attainable. Together, these results suggest that GSPs may represent a potential therapeutic agent for the non-small cell lung cancer. Paper Grape Proanthocyanidins Induce Apoptosis by Loss of Mitochondrial Membrane Potential of Human Non-Small Cell Lung Cancer Cells In Vitro and In Vivo Authors Tripti Singh2, Som D. Sharma2, Santosh K. Katiyar1,2,3,4* 1 Birmingham Veterans Affairs Medical Center, Birmingham, Alabama, United States of America, 2 Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, 3 Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America, 4 Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America Citation: Singh T, Sharma SD, Katiyar SK (2011) Grape Proanthocyanidins Induce Apoptosis by Loss of Mitochondrial Membrane Potential of Human Non-Small Cell Lung Cancer Cells In Vitro and In Vivo. PLoS ONE 6(11): e27444. doi:10.1371/journal.pone.0027444 .Suggested by the author:Lung cancer vaccine prevents cancer progressionUAB finds green tea component that reduces skin cancer spread. 2 SharePrintEmail Continue reading on Examiner.com UAB finds grape extract that kills lung cancer cells - Birmingham science news | Examiner.com http://www.examiner.com/science-news-in ... z1fgmUVJvu

Great news! Thanks for posting

If you email me your at alisa.brenes@gmail.com and send me your email address, I can send you my list and where I get them from ...

Thank you all!!!!! Everyone on the board is an inspiration

Thank you all so much for the well wishes. It is overwhelming how caring you all are. I also feel blessed to have this community! Love, Alisa

Hello cyber family, I haven't been on the boards for a while, between time constraints and recent losses, it's been hard for me to get here. But I just went for my scan - I usually get scanned every 6 months even though the doctor recommended a yearly schedule now, but after 8 months I couldn't take the anxiety of waiting, so I went - and I wanted to share my good news to give others hope. It's been 11 years since surgery and my last chemo treatment and I am still NED (No Evidence of Disease for any newbies) !!!!! I thank God every day for this blessing.

http://www.sciencedaily.com/releases/20 ... 111656.htm Vitamin D Linked to Lung Cancer Survival, Study Suggests ScienceDaily (Mar. 1, 2011) — Recent research suggests vitamin D may be able to stop or prevent cancer. Now, a new study finds an enzyme that plays a role in metabolizing vitamin D can predict lung cancer survival.

http://www.sciencedaily.com/releases/20 ... 082926.htm ScienceDaily (Feb. 26, 2011) — A drug that is currently used to help treat bone metastases in patients with lung cancer could also be useful at an earlier stage of treatment, to prevent the cancer from spreading in the first place, Italian researchers have found.

Treatment of advanced non-small-cell lung cancer with Chinese herbal medicine by stages combined with chemotherapy Treatment of advanced non-small-cell lung cancer with Chinese herbal medicine by stages combined with chemotherapy Journal of Cancer Research & Clinical Oncology, 02/23/2011 Xu ZY et al. – Chinese herbal medicine combined with chemotherapy showed favorable effect in improving quality of life and prolonging survival time on patients with advanced NSCLC.

http://www.mdlinx.com/oncology/newsl-ar ... -cell-lung Supplementation with fish oil increases first-line chemotherapy efficacy in patients with advanced nonsmall cell lung cancer Cancer, 02/17/2011 Clinical Article Murphy RA et al. – This study evaluated whether the combination of FO and chemotherapy (carboplatin with vinorelbine or gemcitabine) provided a benefit over standard of care (SOC) on response rate and clinical benefit from chemotherapy in patients with advanced NSCLC. Compared with SOC, supplementation with FO results in increased chemotherapy efficacy without affecting the toxicity profile and may contribute to increased survival. Methods •Forty-six patients completed the study, n = 31 in the SOC group and n = 15 in the FO group (2.5 g EPA + DHA/day) •Response to chemotherapy was determined by clinical examination and imaging •Response rate defined as sum of CR plus PR •Clinical benefit defined as sum of CR, PR, and stable disease divided by number of patients •Toxicities graded by nurse before each chemotherapy cycle •Survival calculated 1 year after study enrollment Results •Patients in FO group had an increased RR and greater clinical benefit compared with SOC group (60.0% vs 25.8%, P = .008; 80.0% vs 41.9%, P = .02, respectively) •Incidence of dose-limiting toxicity did not differ between groups (P = .46) •One-year survival tended to be greater in FO group (60.0% vs 38.7%; P = .15)

Hi guys, October 24th is the NYC Walk for a Cure for Lung Cancer! Yay! We are growing strong year by year!! LET'S SPREAD THE WORD....... And anyone in the vicinity of NYC, come on and walk with us! http://events.lungevity.org/site/TR?px= ... g=personal LUNGevity Foundation is a 501©(3) nonprofit organization. Your contribution is tax-deductible to the full extent provided by law.

Hello all, it's been a while since I've posted, but I wanted to share my good news with my cyber family. I just had my latest followup CT scan of the chest and I am still stable and considered NED (No Evidence of Disease)!! I feel so blessed. I hope this gives others hope. It has been 10 years since my diagnosis of Stage 3a NSCLC. Blessings to all, Alisa

Monavie is a waste of money. It is watered down Acai. The Acai Berry is a good, healthy berry, but Monavie waters theirs down horribly. Best to get an extract from a more reputable company rather than a multi-level company that needs to recruit and sell to maintain itself ...

I have been reading articles like this and hearing about this for years and keep asking my doctors and they all say it's not ready yet. I hope this means we are getting close. It will be an amazing breakthough!

New lung cancer drug shows dramatic results for shrinking tumors: Phase III clinical trial being offered http://www.sciencedaily.com/releases/20 ... 142603.htm Patients with a specific kind of lung cancer may benefit from a Phase III clinical trial being offered. The new drug, crizotinib, under development by Pfizer, showed dramatic results in reducing lung cancer tumors in some patients during Phase I and II clinical trials.

Hi all. I'm just catching up on the boards. I had to stay away for a bit due to business time constraints and I needed to get my balance back after losing 2 friends to lung cancer the same month (Linda/MeadowBreeze and I would meet for lunch often and her loss was a hard one!). I wanted you all to know I went to Linda's funeral, it was very difficult, but beautiful. There was a lot of love in the room and Linda's daughter, Stacey, who was her caregiver, is hanging in there and the love of her Mom and their relationship keeps her strong.

I take Cell Forte IP-6 with Inositol. You can google it and many hits will show. Take care,