I had the rash pretty severely when I started Iressa last fall...Coincidentally, this is when I experienced the greatest amount of shrinkage in my tumors, but my doctor tells me that there is really no correlation. I've used Aveno creams heavily for relief, the rash has since subsided, and my tumors have been stable since November. Current side effects are occasional, short bursts of diarrhea, frizzy hair, weird breakage and scaling of my fingernails and toenails.
Hope this helps.
Peggy