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Found 5 results

  1. Hello, I recently joined and am really amazed by the info and encouragement here. I was recently diagnosed with NSCLC adenocarcinoma in the lower lobe of right lung, stage IV (both lungs and small spots on my liver). I'm EGFR+ and so my oncologist prescribed Tagrisso, not started yet. Yesterday I was thrown for a loop as he is now recommending that I join a phase 3 trial. The trial has 2 arms, one with Tagrisso alone, the other with Tagrisso + Avastin (ECOG-ACRIN). I read that the phase 2 trials were not really successful, so I'm highly conflicted about joining the trial at this time as I was excited to be starting the Tagrisso. Any thoughts?
  2. Hi Everyone! I had a pretty treatment specific question. My Mom's first line of treatment was Carboplatin and Alimta which she handled VERY well and had a great response to as a chemotherapy drug. As her cancer has recently returned, she's just started her second line treatment which is Carboplatin/Abraxane/Avastin. She only received the Carboplatin and Abraxane during her treatment yesterday as they found some blood in her urine so they didn't want to deliver the Avastin without first culturing that to see what was going on. Does anyone have an experience with this course of treatment (specifically this combination of drugs in 1st and 2nd line treatments)? I'm just curious what she can expect from the Carboplatin/Abraxane combo versus what she experienced with the Carboplatin and Alimta. I know each case and each person is different in terms of how they respond to chemo and what their side effects are (even on the same drug course) and I'm familiar with the side effects that are listed in general from each of these drugs just looking to see if someone here had different experiences with both forms of treatment. I know its pretty specific so I'm not sure that this makes sense, but trying to get a gauge for her from others who have experienced them. Thanks in advance, Maigan
  3. Phase III IMPOWER 150 study showed that Tecentriq (atezolizumab) and Avastin (bevacizumab) plus chemotherapy significantly reduced the risk of disease worsening or death in the initial treatment of people with a type of advanced lung cancer. These data are not fully mature and the next OS analysis is expected in the first half of 2018. They will be submitting these results to health authorities globally (FDA and EMA). You can read more about the study here https://www.gene.com/media/press-releases/14692/2017-11-19/phase-iii-impower150-study-showed-genent
  4. My spouse was diagnosed almost exactly a month ago. Went in for ER visit believing it was a kidney stone causing pain in pelvic area. Through extensive tests and second opinions, it came back as stage 4 non small cell lung cancer (2.6 cm mass) with bone mets to the right pelvic bone (2.7 cm mass). shes currently finishing round 1 of chemo- alimta and carboplatin. The next round will add avastin. Four rounds total followed by radiation. As hopeful as I try to be, she is very doom and gloom. The dr talked at the last visit of when she is remission, and I take that as a sign that the team of Drs wouldn't talk of remission if they didn't believe it was possible. Biopsy of pelvic bone done at ER visit came back as not being The mutation suitable for tarceva, and confirming adenocarcinoma. He talked that if after remission she would relapse the next step would be opdivo. At the initial appointment, she was told that without treatment she would have six months to live. I guess what I am seeking is advice from other spouses/caregivers on how to keep it all together everyday. And if anybody has any survivor stories that they are willing to share- to possibly help her keep hope that there are tomorrows.
  5. Hello, my name is Christine. My, 71 yr old, Mother was diagnosed in Nov 2016 w/ Stage IV metastatic adenocarcinoma NSCLC (primary: right lung, spread to both adrenal glands, brain & right proximal tibia). At diagnosis she was given an estimate of 6-12 months to live, which was quickly adjusted to 6 months after they discovered 13 brain mets opposed to the 3 they originally saw. She had surgery to remove the tumor in her right tibia, which they filled with bone cement to stabilize the bone. She has completed whole brain radiation, radiation to the right tibia & 2 rounds of chemo: Paraplatin (Carboplatin), Alimta (Pemetrexed) & Avastin (Bevacizumab). The chemo was unsuccessful. The cancer spread to multiple bones in her left leg, her pelvis & spine. They stopped chemo & started Opdivo last week. It is too soon after completing whole brain radiation to do another brain scan to know if it helped. I'm sorry for the information overload....I'm just trying to give as much info as possible to see if anyone here has a similar situation & could offer some words of wisdom, offer a glimpse of hope or suggest ways I can help her. Thank you in advance for your help.
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