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Drug Trial - R115777 - Zarnestra


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I posted this question on the Clinical drug Trials forum and another member suggested I ask about it here. I am so happy to have found this site. I've learned so much and I love reading the inspirational stories, they give me lots of hope.

My mom was dx with NSCLC stage IIIB, inoperable.

She has completed 3 rounds of chemo and now her doctor wants her to join a clinical drug trial for a drug R115777 (Zarnestra). This is an oral medication (similar to Iressa) that is supposed to help her with side effects from radiation. It is identified as a farnesyl transferase inhibitor (FTI). Previously, this drug has been used to treat pancreatic cancer, Myeloma and leukemia with some success. By success, I mean that beside fatigue associated with traditional chemo, patients are tolerating this treatment better than traditional chemo. I'm still surfing the web to find out as much as I can. Has anyone heard of this drug?

My mom is so wonderful and I love her so much. I'm hoping for a miracle.

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