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phase 1 trials


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We are considering a phase one trial. Reading the documents is extremely scarey!! We think 1 or 2 groups may have already been through one course of the treatment, so more info may be available, we willbe talking to trial docs on Monday so will learn whole story, but my question is what has been others experience with phase one trials? Trying to weigh the risks and complex schedule required of the trial with possible benefits. My wife has been off treatment since Jan. when we found Iressa had stopped working, but has been feeling great! Because of her history she is supposed to be a very good candidate for this particular trial ( a new protein tyrosine kinase inhibitor from BMS). any experience?

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