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Wood smoke may cause lung cancer in non-smokers

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Wood Smoke May Cause Lung Cancer In Nonsmokers


July 28, 2005

Burning wood may be associated with lung cancer, even with people who do not smoke, suggests a new study.

Javier Delgado and colleagues from the Extracellular Matrix Lab, Calzada de Tlalpan, Mexico, gathered blood samples from 62 patients with lung cancer, 9 patients with chronic obstructive pulmonary disease (COPD) and 9 control subjects. Of the patients with lung cancer, 23 were tobacco smokers (37.1%), 24 were exposed to wood smoke (38.7%) and 15 were not in either category (24.2%).

Study results show that 38.7% of the patients with lung cancer were nonsmokers who were exposed to continuous wood smoke for over 10 years. Most of these people were women living in rural areas, with poverty conditions. The findings not only suggest a connection between lung cancer and exposure to wood smoke but they also indicate that wood smoke may cause similar gene mutations to p53, phospho-p53, and MDM2 protein expression as tobacco use.

The study appeared in Chest (Delgado J, Martinez LM, Sancez TT, et al., Lung cancer pathogenesis associated with wood smoke exposure. 2005;128:124-131).

© 2004 NewsRx.com. All Rights Reserved. ©Copyright 2005, Biotech Week via NewsRx.com

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