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Lung-tumor size linked with cancer spread: study


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http://news.xinhuanet.com/english/2006- ... 177560.htm

BEIJING, Feb. 14(Xinhuanet) -- Lung-tumor size appears to be useful in predicting whether the cancer has spread among patients with asymptomatic lung cancer, U.S. researchers find.

The findings suggest that early screening may be useful in detecting cancers that are still curable, according to a new article in the February 13 issue of Archives of Internal Medicine.

The researchers say although tumor size has been linked to cancer prognosis in patients with symptoms, the relationship between tumor size, metastasis and prognosis in asymptomatic individuals has been unclear.

Doctors at the New York Presbyterian Hospital-Weill Cornell Medical Center and the International Early Lung Cancer Action Program screened 28,689 men and women for lung cancer at 38 institutions worldwide between 1993 and 2004.

A total of 464 cases of lung cancer were screen diagnosed, included 436 "non-small cell" lung cancers and 28 cases of "small cell" lung cancer.

For the 436 patients with "non-small cell" cancers, which are less aggressive than "small-cell" cancers, the likelihood of metastasis increased along with tumor size.

When the researchers analyzed the tumors by consistency, they found the association strongest for solid tumors, weaker for part-solid tumors and not apparent for non-solid tumors.

" The pattern confirmed herein suggests the usefulness of finding latent cancers at small sizes," the authors conclude.

"Most lung cancers without evidence of lymph node metastases are curable, with the curability rate being higher at smaller sizes."

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