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B6 From Consumer Reports Testing

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What other names is the product known by?

Adermine Hydrochloride, B6, B Complex Vitamin, Pyridoxal, Pyridoxamine, Pyridoxine Hydrochloride.

What is it?

Pyridoxine is a vitamin. It can be found in certain foods such as cereals, beans, vegetables, liver, meat, and eggs. It can also be made in a laboratory.

Is it Effective?

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate.

The effectiveness ratings for PYRIDOXINE (VITAMIN B6) are as follows:Effective for...

Treatment and prevention of pyridoxine deficiency.

Treating a type of anemia called sideroblastic anemia.

Treating some types of seizures in infants.

Likely Effective for...

Reducing elevated blood levels of homocysteine, a substance thought to be involved in heart disease.

Possibly Effective for...

Upset stomach and vomiting in pregnancy.

Premenstrual syndrome (PMS).

Behavior disorders in children with low levels of a brain chemical called serotonin.

Kidney stones.

Movement disorders (tardive dyskinesia) in people taking medicines for mental disorders.

Reducing lung cancer risk in men who smoke.

Possibly Ineffective for...


Carpal tunnel syndrome.

Preventing another stroke.

Alzheimer's disease.

Insufficient Evidence to Rate Effectiveness for...

Preventing reblockage of blood vessels after angioplasty, boosting the immune system, muscle cramps, eye problems, kidney problems, night leg cramps, arthritis, allergies, asthma, attention deficit-hyperactivity disorder (ADHD), Lyme disease, and other conditions.

How does it work?

Pyridoxine is required for the proper function of sugars, fats, and proteins in the body. It is also required for the proper growth and development of the brain, nerves, skin, and many other parts of the body.

Are there safety concerns?

Pyridoxine is safe for most people. In some people, pyridoxine might cause nausea, vomiting, stomach pain, loss of appetite, headache, tingling, sleepiness, and other side effects. Long-term use of high doses might cause certain brain and nerve problems.

Pyridoxine is also safe for pregnant or breast-feeding women when taken in the amounts recommended. These amounts are 1.9 mg per day for pregnant women and 2.0 mg per day for breast-feeding women.

Are there any interactions with medications?

Amiodarone (Cordarone):

Amiodarone (Cordarone) might increase your sensitivity to sunlight. Taking vitamin B6 (pyridoxine) along with amiodarone (Cordarone) might increase the chances of sunburn, blistering, or rashes on areas of skin exposed to sunlight. Be sure to wear sunblock and protective clothing when spending time in the sun.


The body breaks down levodopa to get rid of it. Vitamin B6 (pyridoxine) can increase how quickly the body breaks down and gets rid of levodopa. But this is only a problem if you are taking levodopa alone. Most people take levodopa along with carbidopa (Sinemet). Carbidopa prevents this interaction from occurring. If you are taking levodopa without carbidopa do not take vitamin B6.

Phenytoin (Dilantin):

The body breaks down phenytoin (Dilantin) to get rid of it. Pyridoxine (vitamin B6) might increase how quickly the body breaks down phenytoin. Taking pyridoxine (vitamin B6) and taking phenytoin (Dilantin) might decrease the effectiveness of phenytoin (Dilantin) and increase the possibility of seizures. Do not take large doses of pyridoxine (vitamin B6) if you are taking phenytoin (Dilantin).

Phenobarbital (Luminal):

The body breaks down phenobarbital (Luminal) to get rid of it. Pyridoxine might increase how quickly the body breaks down phenobarbital (Luminal). This could decrease the effectiveness of phenobarbital (Luminal).

Information comes from Natural Medicines Comprehensive Database CONSUMER Version

References are found in Natural

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