MsC1210 Posted October 30, 2006 Share Posted October 30, 2006 Air Flow Obstructions May Predict Lung Lesions 30 Oct 2006 New research suggests that airflow obstructions determined by spirometry may predict premalignant lung lesions. Using a cohort of subjects who visited lung cancer screening clinics from 1996 to 2005, researchers from the Roswell Park Cancer Institute in New York analyzed the relationship between spirometric parameters of airflow obstruction and central premalignant lung lesions. All of the patients underwent simple spirometry, and 269 high-risk patients received autoflouorescence bronchoscopy with endobronchial biopsy of suspicious legions. In total, 61 biopsy results were normal, while 123 confirmed either early or invasive central lung cancer. Researchers also found that patients with FEV1 less than 70 percent were associated with almost twice the risk of detecting premalignant or malignant lesions. Researchers suggest that spirometry used with autofluorescence bronchoscopy is a potential marker for lung cancer surveillance. ### CHEST 2006 abstract briefs Contact: Jennifer Stawarz American College of Chest Physicians Article URL: http://www.medicalnewstoday.com/medical ... wsid=55185 Quote Link to comment Share on other sites More sharing options...
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