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Cancer surgery – Celebrex indicated?

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While researching hospitals/surgeons to have my adrenal metastasis removed (adrenalectomy) in California, I ran across the following that seemed interesting to me. Essentially, the studies tell me that Celebrex is useful to minimize the spread of cancer from circulating tumor cells as a result of surgery.

In an abstract: “Surgical manipulation of lung cancers may increase circulating tumor cells and contribute to metastatic recurrence after resection. Cyclooxygenase 2 is overexpressed in most non–small cell lung cancer and upregulates the cell adhesion receptor CD44. Our goal was to examine the effects of perioperative cyclooxygenase blockade on the metastatic potential of circulating tumor cells, CD44 expression, and adhesion of cancer cells to extracellular matrix.


http://jtcs.ctsnetjournals.org/cgi/cont ... /132/2/297

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