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LC Screening with LDCT has false positives

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Lung Cancer Screening with Low Dose Computed Tomography Has High Rate of False Positives

Patients screened for lung cancer recurrence with low dose computer tomography (LDCT) showed more false positive results (meaning that the test shows that cancer is present when follow-up testing finds no cancer) than a chest x-ray, according to a new study.

LDCT scans and chest x-rays are procedures that create a picture of the inside of the body. After one scan, the fals positive rate was 21% for LDCT and 9% for chest x-ray. After two scans, the rates of false positive results increased to 33% with LDCT and 15% for a chest xray.


"All medical tests, including screening tests, have benefits and risks," said lead author Jennifer M. Croswell, MD, Acting Director of the National Institutes of Health Office of Medical Applications of Research.

"We want to give people who are considering lung cancer screening the information they need to make informed decisions about the tests they choose." False-positive test results can lead to additional follow-up testing, invasive procedures, or surgery for the patient. In addition, false-positive results may also cause more anxiety for the patient.

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