Barb73 Posted August 4, 2009 Share Posted August 4, 2009 http://www.reuters.com/article/rbssHeal ... 3320090803 ARTICLE: . . . . . . . . . FRANKFURT, Aug 3 (Reuters) - Boehringer Ingelheim is starting a new Phase III trial of its lung-cancer drug Tovok to show the pill works in patients whose tumours have undergone a certain gene mutation, the company said on Monday. Privately held Boehringer is trying to establish Tovok as an initial treatment for non-small cell lung cancer patients (NSCLC) whose tumours show a mutation of the so-called EGF receptors on the surface of tumour cells, targeting the same market as AstraZeneca's (AZN.L: Quote, Profile, Research, Stock Buzz) Iressa. Iressa last month won approval in Europe for use in the 10 to 15 percent of lung cancer patients whose tumours had undergone the EGFR gene mutation, reviving the fortunes of a product which had largely been written off by industry analysts. Boehringer, Germany's second-largest drugmaker, said it would compare the efficacy and safety of Tovok, based on the active ingredient BIBW 2992, to that of standard chemotherapy of cisplatin and pemetrexed. The company is currently testing Tovok in two further Phase III trials. Tovok and Iressa could also pose a threat to Tarceva, another oral lung cancer treatment from OSI Pharmaceuticals Inc (OSIP.O: Quote, Profile, Research, Stock Buzz) and Roche Holding AG (ROG.VX: Quote, Profile, Research, Stock Buzz). Three phases of testing are generally required for regulatory approval. (Reporting by Ludwig Burger; Editing by David Holmes) . . . . . . . . . (Reuters, Healthcare News, August 3. 2009) Disclaimer: The information contained in these articles may or may not be in agreement with my own opinions. They are not being posted with the intention of being medical advice of any kind. Quote Link to comment Share on other sites More sharing options...
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