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30yr Evaluation of outcomes for NSCLC


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30-Year Evaluation Of The Surgical Outcomes For Non-Small Cell Lung Cancer Concludes Early Diagnosis Key For Improving Survival

16 Jun 2010

Research published in the June edition of the Journal of Thoracic Oncology sought to investigate the time trends of surgical outcomes of patients with non-small cell lung cancer (NSCLC) between 1979 and 2008. The incidence of lung cancer continues to rise; therefore, countermeasures to decrease death rates have become an important public health issue. After analyzing the time trends, researchers postulated that the increase of patients diagnosed with early stages of adenocarcinoma contribute to the favorable prognostic and survival outcomes. Furthermore, the research highlights that prognosis of NSCLC patients has improved in recent years.

The current treatment strategy for NSCLC depends on clinical staging, to which surgical resection is the first-line treatment for stages I to II. Moreover, only a few of the stage III cases are treated surgically. While the standards for surgical treatment have remained unchanged for a few decades, there have been a number of advances in perioperative, anesthetic, and intraoperative management, specifically over the past three decades. To gather insights on the correlation to overall survival, the present study retrospectively investigated the clinicopathologic features of NSCLC patients who underwent surgery and the corresponding time trends of surgical outcomes.

To draw the analysis, researchers reviewed records of nearly 1,500 patients who underwent resection of NSCLC during the following five time intervals: (1) 1979 - 1988, (2) 1989 - 1993, (3) 1994 - 1998, (4) 1999 and (5) 2004. Overall results showed that the number of patients who underwent a resection, the percentage of pathologic stage IA lung cancers, their subsequent survival and the percentage of adenocarcinoma have all progressively increased over the almost 30 year span. The only variable that decreased was tumor size, indicating that diagnoses were increasingly earlier. Most notably survival rates for 1999-2004 and 2004-2008 were significantly better than any of the previous three periods.

"The prognosis of NSCLC patients has been remarkably improved in recent years," explains lead study investigator Takeshi Hanagiri, MD, PhD. "The increase of patients with diagnosed with adenocarcinoma in the early stages is thought to strongly contribute to the favorable results, further reiterating the key factor of early diagnosis for improving the survival of lung cancer patients after surgical treatment. Thus, early diagnosis remains a key factor for improving the survival of lung cancer patients after surgical treatment"


Megan Richter

International Association for the Study of Lung Cancer


Article URL: http://www.medicalnewstoday.com/articles/191901.php

Main News Category: Lung Cancer


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And I must comment on this. I went to a seminar on NSCLC adenocarcinoma. Early detection is the key. And unfortunately lung cancer is pretty asymptomatic. So we must be proactive. He suggested a CT scan (NOT X-ray) for anyone over 50 who worked in an environment that exposed them to toxic fumes, asbestos, or who smoked for more than 20 years if there is a history of cancer in their family.

He further suggested that anyone over the age of 60 with the same factors the same test, with the differential that if you smoked for 25 or more years, you should get the scan regardless of whether you have a family with a history of cancer.

The CT Scan in Michigan is about $250. Well worth the investment in your pro-active health. If you are DX, the CT scan is covered obviously. If not, celebrate!

I had the family history, so I got the scan. No symptoms, so I went to Google and typed in lung cancer symptoms, printed the list and handed it to my doctor and said I have all of these (lied). He looked at me with a grin, having been my doctor for years, and said I'll order the scan.

If I had not done this, I most likely would not still be here today.

I'm so glad I followed my guts in this.

Judy in MI

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