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GemCarbo chemotherapy for lung cancer


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My husband used the GemCarbo when he first began his chemo. I'm sure everyone is different but in his case it was extremely harsh on his system. He had to have blood transfusions after each and every treatment. They stopped this combo and switched him to Tarceva.

This does "not" happen to everyone though. I'm sure others will follow here that have had success.

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Thank you Michelle. Quite surprised that it was not on the site even as a search query.

As a secondary question: does switching from cisplatin to carboplatin mean one will need to have several more chemo trips due to the fact that carboplatin is less effective than cisplatin?

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I responded to your post on another thread, but the number of treatments probably depends on a number of things. I started with cisplatin/etoposide - but was then switched to carboplatin/taxol. I had quite a few more carbo/taxol treatments than had initially been scheduled with the cisplatin/etop. However, I was also having daily radiation at the same time, and I believe that was a factor. The drug combinations themselves also are another factor. I think the answer as to how many can vary from patient to patient, even though there are norms. This should be a question your mother's doctor can answer - although they may not really know the answer to that yet themselves.

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Hi Annie,

most medical questions and specific information on treatments will be within our ask the experts and at GRACE. Like Diane said, there are a certain standard number of treatments that doctors prescribe- those are often taylored to the age of the patient, other health factors, etc... With my dad, he never finished teh standard prescribed treatment. He developed too may issues and side effects to be able to continue more than a couple of weeks. Even so, with only doing 50% of treatment the first time, he saw a huge reduction in his tumors. Everyones different and your mom's doctor will have better answers for you.

While we have posted personal experiences here on the message boards, in 10 years I haven't read about anyone given the opportunity to choose between carbo and cist. I may be mistaken but I think it's just part of the standard of care and research has determined which is most effective when used first and with specific types of lung cancers. The same research that set the standard number of treatments that doctors start off with.

I don't know if any of this helps. My dad used Etopisode and Carbo first, then next line was Cist and Irinotecan. He was one of those patients that experienced a lot of side effects from the "platin" drugs, but on the other hand they were very effective too.

Keep posting and keep us postedon your mom!



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