Hello everyone, My mom was diagnosed with non-small cell lung cancer in March 2018

[LOVEMAMA]

Hello everyone, I am new here. Hope we could help each other.

In early March 2018, my mother was diagnosed with lung cancer adenocarcinoma Stage 4, multiple nodules in the lungs and liver metastasis. On April 24, we did the first chemotherapy with the drugs pemetrexed and carboplatin, after two treatments, lung nodules and liver metastasis the lesions were significantly reduced, the primary original lesions were reduced by 50% and then two other chemotherapy sessions were performed. The protocol was the same as before and the BONE CT scan showed that there were multiple bone turnovers in the whole body, no mutation in the detection (ALL negetive for target treatmet) and the IMMUNE PD1 Keytruda TMB response rate was 10%.

The doctor will use the PD1 Keytruda for the second line treatment for my mother, start from next Friday 27/07/2018.

I love my mother so much and this is like earthquake for me and the family.

Hope she could feel better. Thank you everyone...

[LexieCat]

Hi, Lamprad, and welcome!

I'm so sorry about your mom's diagnosis.  I don't know a whole lot about drug therapies (I had surgery but no drugs/radiation), but lots of folks here do, and they will be along shortly to provide some more knowledgable feedback on the treatment she is receiving.

Glad you found us--this is a great place for support.  

Teri

[LOVEMAMA]

18 minutes ago, LexieCat said:

Hi, Lamprad, and welcome!

I'm so sorry about your mom's diagnosis.  I don't know a whole lot about drug therapies (I had surgery but no drugs/radiation), but lots of folks here do, and they will be along shortly to provide some more knowledgable feedback on the treatment she is receiving.

Glad you found us--this is a great place for support.  

Teri

Thank you very much Teri  I also reviewed your reply in this forum and you have a great hot friendly heart.

You are lucky that you could had the surgery. Most of the lung cancer when it diagnosed, surgery is not an option anymore already.

Most of us down the path of conventional radiation and chemo but now targeted therapy and immunotherapy have become effective weapons to control and hopefully eliminate lung cancer.  

The chemo did a gret job for the lung tumor but the Bone progressed.

I dont know if the PD1 is not work for my mother (her TMB is 10%) what will be the next plan...

Of course I hope it could work for my mother, I pary for her everyday....

Hope you could be happy everyday too

[BridgetO]

Hi and welcome from me too.  A cancer diagnosis IS like an earthquake for the whole family.  I hope the Keytruda works for your mom.

Hang in there,

Bridget O

[LOVEMAMA]

4 minutes ago, BridgetO said:

Hi and welcome from me too.  A cancer diagnosis IS like an earthquake for the whole family.  I hope the Keytruda works for your mom.

Hang in there,

Bridget O

Thank you very much Bridget.... Hope it could work....

[Faithpower]

Welcome!  I was started on Optidivo as a second line in December of 2015. It is still working. PTL!  Immunotherapy is amazing. I don’t know a lot about the difference between Optivido and Keytruda but immunotherapy is making all new statistics!  I pray that it works wonders for your mom  like it has for me. 

[LOVEMAMA]

4 minutes ago, Faithpower said:

Welcome!  I was started on Optidivo as a second line in December of 2015. It is still working. PTL!  Immunotherapy is amazing. I don’t know a lot about the difference between Optivido and Keytruda but immunotherapy is making all new statistics!  I pray that it works wonders for your mom  like it has for me. 

What a great outcome for you Faithpower!

Hope my mother could have the same outcome as yours.

For the bone progress, I hope the immunotherapy could control it too!

[LOVEMAMA]

CT update after 4th chemo:

revisualization of a left hilar mass, resulting in significant narrowing of the upper lobe pulmonary artery and its segmental branches, there is also mild narrowing of the main left and the left lower lobe pulmonary arteries, but this is has significantly improved since the CT in April 2018. The mass encases the left main bronchus resulting in very mild narrowing. it also encases the left upper lobe bronchus with its segmental branches, resulting in obstructing of some of the segmental and sub segmental branches, unchanged, there is further volume loss of the left upper lobe since the previous examination, the mass is difficult to measure due to its irregular shape, but may have slightly enlarged since the examination in May.

The main left hilar mass seems to have enlarge since the previous examination. Ne pulmonary nodules are seen in the left upper lobe. The rest of the numerous pulmonary nodules have mostly remained stable, although a few has slightly enlarged the interval.

Mediastina lymph ns have some remained stable and some enlarged in interval.

Metastatic hepatic lesions have some remained stable and some enlarged.

Metastatic disease to the bones has progressed in the interval.

Pathologic fractures visualized in the left iliac bone and around posterior arch the left 3rd rib.

 

Will start the 1st treatment of the Keytura this afternoon at 3:00PM

[Roz]

Wishing your mom all the best with the treatment and hope for positive results from the Keytruda!!

 

Ro

[LOVEMAMA]

Thanks Roz,

I am realy worried about the Pathologic fractures visualized in the left iliac bone and around posterior arch the left 3rd rib.

Any one have any advice about it?

[LexieCat]

I know Judy M. has been dealing with bone mets.  I'm sure she will be along in a bit to share about her experience.  Some of her treatment was pretty painful, but her doctors have a plan, and she's soon going to be seeing an ortho specialist.  

Some folks have had great results from Keytruda--hope it works for your mom.

[LOVEMAMA]

49 minutes ago, LexieCat said:

I know Judy M. has been dealing with bone mets.  I'm sure she will be along in a bit to share about her experience.  Some of her treatment was pretty painful, but her doctors have a plan, and she's soon going to be seeing an ortho specialist.  

Some folks have had great results from Keytruda--hope it works for your mom.

Thank you very much Lexie, hope Keytruda could do the MAGIC!