jack14 Posted August 19, 2020 Share Posted August 19, 2020 Has anyone on Keytruda had night sweats? I have had several lately and was wondering. They are particularly odd, in that I am not feeling hot, and I am in a cool room with a fan blowing and light bedding. I just wake up and throw the cover back and I find myself drenched! No fever, chills, or other signs / symptoms, either. I have been noticing that my TSH has been slowly increasing over the past two treatments though, and I wonder if it could be a thyroid problem? I am up for my seventh infusion Friday. Jul 31, 2020 5.88 uIU/mL (0.5-4.67 uIU/mL ) Jun 22, 2020 4.91 uIU/mL Jun 01, 2020 4.55 uIU/mL May 08, 2020 4.74 uIU/mL Quote Link to comment Share on other sites More sharing options...
jack14 Posted August 19, 2020 Author Share Posted August 19, 2020 PS I am finding conflicting information in regards to what is normal. The Cleveland clinic says normal range for an adult: 0.4 – 5.5 mU/mL while the Amercan Association of Endocrinology says 0.27-4.2 mIU/L . And some thers even say over 10.0 mU/mL is indicative of disease? Quote Link to comment Share on other sites More sharing options...
Sabacat Posted August 19, 2020 Share Posted August 19, 2020 Hey Jack - Don't know about the Keytruda, but your TSH is high by almost all traditional standards, which indicates HYPOthyroidism. In my experience (I have been hypo for 40+ years), you will normally feel cold when that occurs. Surprised no one has suggested medication since that 7/31 reading. When on correct medication (which has evolved over the years), mine stays around 1.0. If it gets above 1.5, I start to have symptoms. Thyroid is a touchy thing and a good endocrinologist will treat the patient, not just the numbers. Best, Susan jack14 1 Quote Link to comment Share on other sites More sharing options...
Deb W Posted August 19, 2020 Share Posted August 19, 2020 Hi Jack, I've been on the triplet for 12 weeks and now Alimta and Keytruda. I have not experienced night sweats. Your TSH seems quite high. jack14 1 Quote Link to comment Share on other sites More sharing options...
Rower Michelle Posted August 19, 2020 Share Posted August 19, 2020 Hi Jack, I had terrible night sweats on Keytruda, even though I only received one dose of the triplet. I was more soaked than menopause sweats, I kept a change of clothes on the night stand to change into during the night. Not a lot that could have been done except nap during the day from disrupted sleep. Stinks! Michelle jack14 1 Quote Link to comment Share on other sites More sharing options...
GaryG Posted August 19, 2020 Share Posted August 19, 2020 I am on the triplet and I experienced night sweats for about one week and changed shirts 3 times/night then they went away. jack14 1 Quote Link to comment Share on other sites More sharing options...
jack14 Posted August 20, 2020 Author Share Posted August 20, 2020 My Onc said something about watching my TSH level awhile back. I think she said that since I wasn't having any issues or symptoms they preferred to watch it. I will let them know about the sweats. Thanks everyone. Quote Link to comment Share on other sites More sharing options...
jack14 Posted August 22, 2020 Author Share Posted August 22, 2020 I pulled my TSH levels from my VA Medical records today to take them to the Oncologist so that she could get the big picture. I was surprised, seems I have been up and down since 2003. 08/01/2019: TSH 3.97 High uIU/mL (0.34-3.77) 09/27/2018: TSH 5.39 H uIU/mL 0.34-3.77 04/10/2018: TSH 7.83 High uIU/mL 0.34-3.77 03/07/2017: TSH 4.74 High uIU/mL (0.34-3.77) 11/27/2012: TSH 3.94 High uIU/mL (0.34-3.77) 12/11/2012: TSH 3.87 High uIU/mL (0.34-3.77) 08/26/2003: TSH 2.08 uIU/mL (.34-4.8) So after the PA at the center that was on duty postphones my infusion today because she wants to make sure my redned eye and three nights of night sweats earlier in the week isn't Covid 19! Oh joy....so, I mention the elevated TSH level and she says they don't look at starting therapy unless it is is 7 or more consistenly. smh I miss my Onc and her PA. Quote Link to comment Share on other sites More sharing options...
Babs Posted August 22, 2020 Share Posted August 22, 2020 Good morning, This is interesting... I just restarted treatment yesterday with Carb/Taxol (which I’ve had before) and new to me Keytruda. I haven’t had ANY kind of treatments since mid June. I had terrible night sweats last night. My cotton PJ top was soaking wet. I just checked my TSH level from yesterday before treatment and it is 0.90 which to me seems well within normal? I just hope this doesn’t go on too long. I don’t have another treatment for 3 weeks. Take care everybody, Babs jack14 1 Quote Link to comment Share on other sites More sharing options...
Deb W Posted August 22, 2020 Share Posted August 22, 2020 Hi Jack, Update...I was put on maintenance of Keytruda and Alimta 10 days ago. I did not experience nights sweats until last night! I didn't have night sweats when it was carbo/alimta/keytruda. Still glad I don't have Carbo now, but I have noticed there are new and different side effects (stomach cramping) with the Keytruda/Alimta dose. Deb Rower Michelle, GaryG and jack14 3 Quote Link to comment Share on other sites More sharing options...
jack14 Posted August 22, 2020 Author Share Posted August 22, 2020 Gee, I wonder if Merck may have alterred the formula or something? Or, more likely, these episodes of night sweats are not related to the drug at all. Oh well, I suppose, unless there is an underlying cause, like an infection or hormonal imbalance or something revealed, then it is just something to endure. I suppose maybe one who suffers this to the extreme, might be wise to pay a little added attention to personal hygiene, electrolytes, and hydration. Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You can post now and register later. If you have an account, sign in now to post with your account.