TD1 Posted January 31, 2021 Share Posted January 31, 2021 Looking for others with MET EXON 14 skipping. I have stage IV now stage IIIA nsclc, adenocarcinoma. Had a 15 cm tumor with all right side mediastinum lymph nodes involved and a few nodules in the right pleura. MET Amplification. SUV max pre-treatment 25.9. Poorly differentiated adenocarcinoma. Was treated with crizotinib, had excellent results with 60 % shrinkage after a few months. I had a right pneumonectomy in April 2018 and had a pathologic complete response. Crizotinib was my only treatment. I didn't have chemotherapy. I stopped taking crizotinib one month post pneumonectomy and a few cancerous nodules reappeared on my right side between two ribs.. I had SBRT True Beam radiation and apparently, it was also successful. I went back on crizotinib and so far my scans have been clear. There is a group called MET CRUSADERS and they can be found at METcrusaders.org and on facebook for anyone who would like more information on the latest treatments and to discuss with others with MET exon 14... I have continued working and still work full time, apart from the surgery and post surgery. I was basically given my life back.. From some of the literature I seem to find that you get better results with targeted therapy with higher amplification... am I wrong? GaryG 1 Quote Link to comment Share on other sites More sharing options...
Join the conversation
You can post now and register later. If you have an account, sign in now to post with your account.