TJM 1,006 Posted February 16 Share Posted February 16 I may be being to hopeful here, but it seems to me that Keytruda is being used on more patients than just with high PDL. Mine is less than 1%. If I get a reoccurrence should I push for that? My onc doesn't think out of the box much Peace Tom Link to post Share on other sites
Tom Galli 4,330 Posted February 16 Share Posted February 16 Tom, I’m not an expert but I think immunotherapy can be most effective for both high and low range PDL-1 expressions. But with the flood of new drugs and combinations, it is likely best to check in with your doc. You can’t believe the cold & snow in Texas. Lost power at 2 AM this morning. A foot of snow on the ground. Just now got an internet connection. Cell towers not working. Nightmare! Stay the course. Tom (chilled in Texas) Link to post Share on other sites
TJM 1,006 Posted February 16 Author Share Posted February 16 Thx Tom 10" outside my door. Raining now so here comes the mess. Peace Tom Link to post Share on other sites
GaryG 846 Posted February 16 Share Posted February 16 Tom (TJM): Yes Keytruda is used on high and low PDL-1 levels but the caveat here "in conjunction with other drugs. Yet the jury is still out on the effectiveness of immunotherapy in general for the long run. I asked that same question of my oncologist and some prefer it to target therapy and radiation. The next few years will shed more lights and hopefully they will be bright. TJM 1 Link to post Share on other sites
LexieCat 4,339 Posted February 16 Share Posted February 16 Ditto--I have 5% PDL-1 and my oncologist said anything above zero is appropriate for immunotherapy. I think with higher levels the result might be more dramatic, but anything that helps beat back the cancer (without excessively beating up the patient) has to be a good thing. GramaA and TJM 2 Link to post Share on other sites
LexieCat 4,339 Posted February 16 Share Posted February 16 8 hours ago, Tom Galli said: You can’t believe the cold & snow in Texas. Lost power at 2 AM this morning. A foot of snow on the ground. Just now got an internet connection. Cell towers not working. Nightmare! I hate to say it, but the temp right now in South Jersey is 51 degrees! I feel for you folks who are normally in the warmer climes, having to deal with this stuff. We may be getting more snow later this week, but not more than a couple of inches. Hopefully with the warm temps today, and the predicted rain, we'll be rid of some of the accumulation from before. Stay warm and stay safe! Link to post Share on other sites
Deb W 401 Posted February 16 Share Posted February 16 Hi Tom, I had a recurrence and PDL of less than 10% and Keytruda worked for me. Good luck. Deb TJM, GaryG and GramaA 2 1 Link to post Share on other sites
TJM 1,006 Posted February 16 Author Share Posted February 16 Thanks to all. Gives me something to talk about with my oncologist. Going to schedule my next scan today. Let the anxiety begin. Peace Tom GaryG and Tom Galli 2 Link to post Share on other sites
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