LexieCat Posted April 15, 2021 Share Posted April 15, 2021 So the cancer HAS progressed. Per yesterday's scans, the primary tumor has grown slightly, as have at least some of the lymph nodes. My oncologist was reviewing the scans for the first time while I sat there--apparently because my scan wasn't reviewed by the radiologist until afternoon, it wasn't there when he was reviewing the charts for today's visits. He said, "It's not a lot of progression." I said, "Isn't that like being 'a little bit pregnant'?" and he said no, in terms of prognosis this was a whole lot better than seeing an "explosion" of progression. The question was where to go from here. He's recommending a clinical trial that involves infusions of Keytruda and another brand new immunotherapy drug, named for now as CAN04, described as "a fully humanized Anti-IL1RAP monoclonal antibody." It sounds like a pretty complicated schedule, with the first several weeks having weekly infusions, and eventually back to every three weeks. And some infusions are with both drugs, while some are just Keytuda. Apparently this second drug is like a "booster" for the Keytruda. It's a Swedish drug and it's a Phase I trial, non-randomized, so everyone gets the new drug. No more Alimta, either--just the two immunotherapy drugs. He brought in the nurse who coordinates for the study. I have to be formally approved, but I meet all the criteria so they don't see any problem with my being accepted. I also need to have another biopsy via bronchoscopy. I asked about a PET-CT, but he sees no point because there were no signs of mets anywhere else on yesterday's scans. So no drugs for me today. They said they like to get most of the previous drugs out of the system so they are starting with a blank slate. Hopefully I can schedule the bronchoscopy soon--they were guessing it might be another 3-4 weeks before I start the trial. Obviously, this is a bummer. I can't say I'm totally shocked after the equivocal scan I had last time, but still disappointing. I'm doing OK, though--as the doc said, something like this almost always happens sooner or later, and I have a lot of confidence in his judgement. So I'll be wading through the 30-page consent document that explains everything, over the next few days--I'll have to come in and sign it once I'm formally accepted. And his SUGGESTION was that I try to have my ophthalmology procedure (the laser thing, if I'm having that done) before we start the trial. So I'll call my ophthalmologist today and have the scheduling person pass that info to the surgeon (who sees patients in that office on Thursdays). Thanks for all the good vibes you all sent--they were good for my spirits! ChiMama, TJM, Sandy N and 1 other 4 Quote Link to comment Share on other sites More sharing options...
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