Jump to content

Research of NS NSCLC with no drivers.


KOP

Recommended Posts

Forum to discuss treatments, Clinical Trials, and research for Non Squamous NSCLC with no drivers and no response from PDL-1 focused immunotherapy. 

Link to comment
Share on other sites

No maintenance so far. I did Chemo and radiation which shrunk the main tumor and lymph nodes. Originally I was told that the cancer had spread and I wasn’t a candidate for surgery. I ended up having such good results that I was able to have an open lobectomy. The surgeon removed upper left lobe and lymph nodes that had been cancerous. That was Oct 2018. I’ve had regular my CT scans and thanks to god and science I’ve been NED. 
 

Link to comment
Share on other sites

Can anybody tell me if one I/O for PDL1 checkpoint didn’t work, does that mean all of them won’t work for a given patient?  They keep coming out with new ones.  I’m told they all work the same.  If that is the case why do we keep seeing more reports on different ones? 

Link to comment
Share on other sites

This is my bro also.  Stage 4 NSCLC with no targetable mutations and negative PDL-1 response.  Dx May 2021.  5 treatments of Carbo/Pem/Pex triplet, targeted radiation to 18 brain tumors on 10/5.  Now off the Carbo and just the Alimta & Keytruda infusions every 3 weeks.  Next scans tomorrow.  Still has a chronic cough and more bad days than good of late with pain, fatigue, and cough.  Also has spread to spine.  

Link to comment
Share on other sites

Sorry to hear.  Just said a prayer for both of you and your families.   Did he show any response to any of his treatments?

Link to comment
Share on other sites

Does anybody have any data or reports on CD66B as a bio marker? I have seen an short article on it being an indicator of poor Immunotherapy response in patients with NSCLC.

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Restore formatting

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

×
×
  • Create New...