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VAccine


cathyjack

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Here are 11 trials found at www.clinicaltrials.gov

http://www.clinicaltrials.gov/ct/search ... ne%2Cnsclc

There may be more trials. You can ask your doctor. Geoff on this board knows of some Dendritic cell vaccines.

Dendritic cells are the cells that act like "WANTED" posters at the post office. They allow the body to detect a foreign cell "non self" and lead the attack. They have memory in a sense.

The problem as you may know with cancer is that the body can not determine "self" from "non self (cancer)" so there is no immune response.

Dendritic cell vaccines like others train the body to recognize the cancer.

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John

I have seen it a few times, so I thought I would ask. Why would it take 5 years to recruit patients. One of these trials has been recruiting since July of 1999? I have seen others that are ongoing for several years, as far as recruitment, too. How can they ever finish a trial, if recruitment takes that long?

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I am currently on the HyperAcute Lung Cancer vacine with the NIH, I agree the best sourch of clinical trials, including vacines are the lists at the site through the NIH. clinicaltrials.gov I believe, I have had no real side effects, very slight at best. My cancer is still stable and the long term effects are still unknown. This is a Phase I trial. Research. and then be persistant if you relly are intersted, is my best advice. I wish you the best of luck .... Prayers for us all.....

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Elaine,

I think people are scared of trials and a sometimes doctors don't know they are there. Not sure. One problem could be the bad press that trials are getting as far as disclosure of bad trials. There are so many restrictions on entry to trials and sometimes it is a pain to actually find one if you are not in a big city. Maybe if the clinical trial system could be more accomodating to some extent (without jepordizing the results) that would help

I think personally it does not make sense to restrict someone from entering a EGFR trials when they have failed a previous one. My thinking is - since they are different drugs and thus different chemical structures (ways of working) why can't a patient try another EGFR drug?

Of course you want there to be a good possibility that it works but what if there is nothing else available.

Soon there is supposed to be a database of all the trials results. Currently, it is pretty hard to get really good data on results and I think for almost everyone very had to interpret.

My mom went in a trial because she thought it might help her but ALSO in the long run it would hopefully help someone else.

John

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