My husband, Jim, did not respond to first, second, or third line chemotherapy & radiation. (He had minimal response to first line chemo of carboplatin / taxol). He is on his final option for treatment...which is TARCEVA. Thank God, he DID have some response to it...has stabalized his tumors (lung & mets to left hip). How long can the Tarceva work? Anybody been on this board been on it for awhile?