Well, I certainly don't like the sound of that, and I especially didn't like reading it in the "impressions" part of the radiologist's report I received Friday summarizing the previous Wednesday's PET scan. Though hardly a surprise given a thoracic surgeon's description of my original PET scan 11 and 1/2 years ago: "You lit that thing up like a Christmas tree." Still, I would have rather read something a bit less ominous. But I don't suppose being diagnosed with two types of cancer (non-small ce
Whether or not I'm certain about my attitude toward being a dual cancer threat (non-small cell lung and papillary thyroid, cancer), only my subconscious knows for sure. This was recently made clear to when I provided my supermarket shopping preferences to my wife, Dina, who for reasons she takes very seriously (my health) won't let me go into stores to buy anything. Ergo, my list. And I may add, there is much adieu about those preferences. It's like a negotiation. Though not exactly partisan, th
Sunday, July 26, 2020
Histological subtyping of lung cancer is still clinically important, said Ignacio I. Wistuba, MD. However, additional parameters such as driver alterations, alternative methods for molecular testing, and immunotherapy-related biomarkers have strengthened the diagnostic and treatment paradigms in lung cancer.
The diagnostic algorithm for lung can
"Thyroid cancer." Again? I thought the point of last week's surgical biopsy was to genetically-sequence a lung cancer tumor. Now you tell me the radiologist/pathologist found more thyroid cancer. As it already has happened, my oncologist - in coordination with my endocrinologist, said that my most recent CT scan showed "excellent results" (from my previous thyroid cancer treatment - which ended with radioiodine therapy), and furthermore noted that the thyroid cancer was confined to my neck. Yet
After more than six months away from the infusion center, due to the treatment for my papillary thyroid cancer stage II, I make my return on Wednesday, July 22. My non-small cell lung cancer stage IV, for which I have been treated since early March 2009, once again becomes front and center after having been back-burnered since early January while we addressed my thyroid cancer. Out of an abundance of caution and concern for the risk of miscellaneous drug/treatment interactions, both cancers coul
By EH News Bureau On Jul 17, 2020
Researchers at Scotland-based University of Dundee have demonstrated a new method of destroying an ‘undruggable’ protein known to play a role in cancer, raising the possibility of a new therapeutic approach to the disease.
Mutations of the K-Ras protein have long been known to cause many cancers, including lung, colorecta
And not just Tuesday, either. All week in fact, I'll be waiting to hear the music. One day, I'll hear from my oncologist and on another day, I'll hear from my endocrinologist. What I'll hear first is the status of my underlying non-small cell lung cancer, stage IV (diagnosed Feb. 2009) and later in the week, I'll get results concerning my most recent party crasher: papillary thyroid cancer, stage II, diagnosed Jan. 2020. This will be the first time I will have been waiting for results simultaneo
July 07, 2020
Individuals with a smoking history should begin annual screening for lung cancer at age 50 years instead of age 55 years, according to a draft recommendation issued by the U.S. Preventive Services Task Force.
The recommendation, an update of USPSTF guidance on lung cancer screening issued 7 years ago, also reduces smoking pack-year elig
"Very interesting," to quote Artie Johnson from "Rowan & Martin's Laugh-In," that "crazy-kooky" comedy show from the 70s. What's interesting is what my oncologist will say concerning the July 6th CT scan of my upper torso (lungs), the first such scan I will have had in almost six months. That interval being twice the usual and customary three month schedule I've been on for years. The reason for this abnormally long interval? As you regular readers know, I was being treated for my second can
We had to euthanize Biscuit, our oldest cat on Saturday, June 20th. He would have been 14 on September 20th. Biscuit is survived by his half-brother, Andrew and his two half sisters, Sloane and Twinkle. Biscuit's litter mate and brother, "Chino" preceded him in death in November, 2019, after succumbing to diabetes. Biscuit had likewise been diagnosed with diabetes around the same time as "Chino." However, as occasionally happens, according to Biscuit's veterinarian, some cats "spontaneously" ove
By Nicole Viviano
June 25, 2020
Biking across the United States is a memorable feat for anyone. One endurance athlete from Lawrenceville managed to complete the Southern Tier bike route while facing down an even greater obstacle: Stage 4 lung cancer.
Isabella de la Houssaye, 56, has lived an active lifestyle, from mountain climbing to Ironman triathlons. Her love of
For those of us living in states where mask-wearing is mostly mandatory (indoors: yes, outdoors: not nearly as much), it is very easy to hide one's emotions. If your mouth is undercover, and being that it is located under your nose and above your chin, it most definitely is, communicating with the public has become strictly verbal. Body language as personified by the expression on one's face has become non grata. All that remains above the mask are your eyes and - to a much lesser effect - your
Apparently, I'm back in the lung cancer business. According to the video visit I had June 8 with my endocrinologist, my thyroid cancer has not moved into my lungs where my oncologist thought it might have - given the results of a previous biopsy and some surprising tumor inactivity in my lungs. The 'surprising inactivity:' the tumors didn't kill me. Living, as they say, is the best reward. And it sure beats the alternative.
Nevertheless, I can't say I'm thrilled with the outcome. All the tu
Roy S. Herbst MD, PhD, discusses the ADAURA trial and the impressive data seen with adjuvant osimertinib and highlights ongoing research efforts being made with the agent in lung cancer.
JUNE 16, 2020
The significant and clinically meaningful improvement in disease-free survival (DFS) demonstrated with adjuvant osimertinib (Tagrisso) in patients with EGFR-mutated, stage I, II, an
Original article post on Jun 09, 2020 on Precision Oncology News
NEW YORK – Revolution Medicines announced today that it has dosed the first patient in a Phase Ib clinical trial evaluating its investigational SHP2 inhibitor, RMC-4630, in combination with Amgen's KRAS G12C inhibitor AMG510.
The open-label, dose escalation and expansion study, sponsored and conducted by Amgen, is evaluating the combination in patients with advanced solid tumors characterized by KRAS G12C mutations. Revol
... is greatly exaggerated." So said Mark Twain. So said W.C. Fields. And so said Kenny Lourie. And the reason I am now saying it is because of what correspondence I received in my personal inbox accessed through my HMO's online site. What I received was a condolence letter (sort of a form letter, quite frankly), addressed to the Lourie family from my oncologist expressing his sadness at my "passing" and his "privilege to have participated in the care of Kenneth Blacker Lourie" (me). Then, a bit
That wasn't so bad. Approximately 29 hours in the hospital in a private room and all I had to do was drink as much water as possible and shower half a dozen times. The goal being to rid myself of the radioiodine I had been given at the beginning of my admission. This "therapy" is used to measure the iodine related to my papillary thyroid cancer and to determine presumably, whether in fact the tumors in my lungs are thyroid cancer which has moved, whether it's still lung cancer, or both.
I haven't been on here much in the last few months, maybe a year. Work kept me much busier than usual but I *think* that is going to finally level out now that we've hired a new director and a couple of additional consultants. I also find it more difficult to break away from my work when my daily commute is now just a walk down the hall. I'm fortunate - and I know it - because I've been able to continue working without interruption. My employer has offices in CA, FL, NJ, OH, and TX and all of ou
In two days I will have completed four weeks on my low iodine diet (no chocolate, no salt, no dairy, no bread) with four days remaining until my one-night hospital admission and subsequent seven-day medical quarantine at home. If I remember correctly, the substance of the hour-long phone conversation we had with a doctor from the Nuclear Medicine department previous to my beginning this thyroid cancer treatment process, on Friday--the day after my "radioiodine therapy"--my eating can return to i
Nearly three weeks into my low iodine diet, in preparation for my hospital overnight on May 28 when I will get my radioactive iodine therapy to be followed immediately by a medical quarantine at home for a week, I wouldn't say I'm thriving. More like persevering. I can't really satiate eating "rabbit" food and what culinary pleasures I can enjoy, I can only have them in small quantities and infrequently at that. I won't give you a list, but just consider what any 10-year-old likes to eat.
After six weeks or so of isolating at home and working hardly at all, I believe it's time to invoke Violet Crawley (aka Maggie Smith), "the Dowager Countess of Grantham," and wonder aloud: "What's a weekend?" Every day feels like some other day or no day at all because the days in and of themselves are meaningless/indistinguishable. I mean, you can't go anywhere, you can't do anything; thankfully, you can use your phone and access your computer, but at the end of the same-old-day, you're basical
AI can categorize lung nodules' cancer risk, study suggests
A new artificial intelligence algorithm can accurately assess the risk of cancer associated with indeterminate pulmonary nodules in patients' lungs, according to a study published in American Journal of Respiratory and Critical Care Medicine.
Traditionally, physicians use CT scans to assess lung nodules, which can lead to earlier cancer diagnoses. However, this approach can also lead to overtreatment if nodule
Sheltering in place while isolating at home, like so many others are, in Maryland, where non-essential businesses remain closed, means life has mostly come to a screeching halt. And unlike Georgia and nearly 30 other common-sense offenders, salons - among many other trying-to-get-going concerns, are not open. Moreover, given the social-distancing guidelines and the stay-at-home mandate, it's unlikely I'll be receiving any service providers in my home either. And considering that I'm not running