[New here & to cancer.]

Kurt (nuckscelts),

I'm sorry this is happening to him.

Can you be more specific about what kind of lung cancer it is? At one point you say its Cancer of Unknown Primary (which would mean they don't know if it's really originated from the lung), and at another you said it is a type from the Non-Small Cell Lung Cancer (NSCLC) category, and you also described fast progression that sounded more like small cell rebounding after initially responding well to chemo.

So can you be more specific? Is it adenocarcinoma, or squamous cell, or large cell, or small cell, or something else?

If it really is a type from the NSCLC category, what tests have been done to determine it's driving mutation and what were the results? E.g., EGFR, and maybe ALK, ROS1, and KRAS for some specific types.

Best hopes,

Craig in PA

[Trial: .....the prevention & treatment of muscle wasting ..]

The big question for drugs like this is whether they don't just help muscle cells survive but cancer cells, too. That was the problem with fish oil supplements -- seemed to stop muscle wasting in one study but according to a lab study of biochemical products in mice models the interaction with platinum-based chemo created chemicals that might enable the cancer to resist the chemo. I think the researchers should be aware of this and may be able to comment on what has been seen in prior studies and pre-clinical research on that question.

Best hopes,