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jenwo

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  1. Like
    jenwo got a reaction from Tom Galli in Any Pancoast survivors/stories?   
    huj123,
    I too have NSCLC Adenocarcinoma with an ERBB2 (HER2) Exon 20 mutation.  It is a small subset, so there aren't any targeted drugs approved at this time.  I had a second opinion at MDAnderson and he spoke of Trastuzumab Deruxtecan having very positive results in NSCLC HER2+ patients. It is approved in breast and gastric cancers and is seeking approval in NSCLC.  The trials available now are only 2nd line, but I would be sure to ask her oncologist about it.  I am starting my chemo next week and hopefully will see some relief from the back and hip pain - where my bone mets are - and not too many side effects of the chemo.  Keep fighting.
  2. Like
    jenwo got a reaction from LexieCat in Any Pancoast survivors/stories?   
    huj123,
    I too have NSCLC Adenocarcinoma with an ERBB2 (HER2) Exon 20 mutation.  It is a small subset, so there aren't any targeted drugs approved at this time.  I had a second opinion at MDAnderson and he spoke of Trastuzumab Deruxtecan having very positive results in NSCLC HER2+ patients. It is approved in breast and gastric cancers and is seeking approval in NSCLC.  The trials available now are only 2nd line, but I would be sure to ask her oncologist about it.  I am starting my chemo next week and hopefully will see some relief from the back and hip pain - where my bone mets are - and not too many side effects of the chemo.  Keep fighting.
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