If you dont mind listening, i would like to tell you my moms story and see what you think. June of 2002 she was dx with extensive sc mets to adrenal. They only biopsy'd the lung and said they made an EDUCATED ASSUMPTION that adrenal was a mets from the lung. This was at a hospital in nj. We took all her records to Sloan Ketering in NY and they said they would use the same protocol. Her onc is in nj but trained at Sloan Kettering. She did 6 rounds of chemo(Cis-Plat) and then had a PET. It still showed activity in the lung and a little activity on the chest(thoracic area), but nothing on the adrenal. Right away the dr called and said we are going to clear this up with radiation. She had 6 weeks of radiation. The dr said wait 2 weeks and go for a CAT. My mom argued and said she wanted a PET, he said fine but he usually doesnt like to do this because sometimes they find activity in different places and doesnt know what to do with that info. She went for 2nd PET and they saw minimal activity on the lung but mass was the same size Pre-radiation.(4.2cm) and increase activity on the chest, but no mass. He suggested taking 2 months off and then another cat. He said she feels too good right now and to give her another chemo would make her feel weak. Personally, I think she was misdiagnosed from the beginning and i had alot of questions for him. Tell me if I am way off please! If she had extensive with mets to adrenal how can chemo alone kill every cancer cell on the adrenal. I asked him if that was possible, and he said chemo alone can shrink it off of an x-ray, but not a pet. Then how could this show no activity. Then he went on to say well she would have the same tx plan anyway. If she was dx w limited sc they would have done chemo and rad. at the same time, no? There is nothing we can do now, but i am just pissed about educated assumptions, because when you are dealing with lives everything should be done exact. They should automatically do biopsy's on every single mass no matter what statistics show. My mom has been off chemo for a total of 5 months and everything is pretty much stabile. According to statistics this should have spread like wildfire already, right? I am so confused. Thank you for listening. i just love my mom so much and wish i could take this all away. It is almost unbelievable. She feels too good!