annie1129 Posted January 18, 2005 Share Posted January 18, 2005 I've posted this in "Ask the Expert" forum before; however, no response has yet received but I do urgently need advices/experience shared by other people. My father is having WBR (2 times per day for 5 consecutive days; total 5 weeks) + temodar (140mg per day) Treatment will be completed next week. However, we got 2 different opinions from 2 oncs for coming treatment. One is - take the temodar for 5 consecutive days (300mg per day) then rest for 23 days, which represent one cycle. Total 5 cycles. Another is - no need to take temodar again as the onc thinks it only helps getting a better result when having the radiation. but it's useless if taking it alone for brain mets. If anyone hv similar experience or advices, please share. Thanks very much. Quote Link to comment Share on other sites More sharing options...
karenl Posted January 19, 2005 Share Posted January 19, 2005 Hi Annie I have just been doing some research on this topic as Mum is commencing WBR tomorrow, and I wanted her to ask the oncologist about Temodar. In my limited reading thus far, it seems that the jury is still out on the benefits of ongoing use of Temodar. I think there has been some suggestion that it will help to prevent recurrence. I think most studies found that using it as a single agent, without WBR, had no therapeutic benefit, but as I said, some are recommending continuation to inhibit recurrence following WBR. Unfortunately, I think it might be one of those times where you need to do your own research, discuss your findings with the Oncologist, and then make a decision as to what you want to do. All the best. By the way, did you get my PM concerning the WBR schedule that your father is having. I am curious about it, as my Mum is having WBR once a day for 10 days, and that is all. Cheers, Karen Quote Link to comment Share on other sites More sharing options...
annie1129 Posted January 19, 2005 Author Share Posted January 19, 2005 Karen, thanks for ur reply. I sent u a PM yesterday. Pls check. If u hvn't received it, pls let me know. Quote Link to comment Share on other sites More sharing options...
john Posted January 19, 2005 Share Posted January 19, 2005 I think it is usually used with WBR, but Gina's? husband received it by itself at Fox Chase. The study below says there was a 24% response rate in patients with NSCLC. Temodar is fairly effective in glioma's (brain cancer) and brain metastasis from melanoma http://www.asco.org/ac/1,1003,_12-00264 ... 987,00.asp http://theoncologist.alphamedpress.org/ ... oncologist Quote Link to comment Share on other sites More sharing options...
john Posted January 19, 2005 Share Posted January 19, 2005 more info http://www.lungcanceronline.org/treatme ... omide.html Quote Link to comment Share on other sites More sharing options...
annie1129 Posted January 22, 2005 Author Share Posted January 22, 2005 Thanks a lot for ur reply. Quote Link to comment Share on other sites More sharing options...
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