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Autofluorescence Bronchoscopy Re Early-Stage Lung Cancer

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Lung cancer: Reduction of mortality by autofluorescence bronchoscopy

The prognosis of lung cancer depends on the stage of disease at diagnosis. Long-term survival is associated with resectable early stage disease. But the majority of centrally located early lesions are missed by conventional bronchoscopy. Autofluorescence bronchoscopy can detect and localize central early malignant changes much better and will be more effective if carried out in high-risk-patients and/or embedded in a program of sputum evaluation and CT examination, Dr. Franz Stanzel (München) reports. He describes the reduction of mortality as a result of such efforts.

"Fluorescence bronchoscopy as a highly sensitive test detects lung cancer at an early stage. The results of the first randomized autofluorescence bronchoscopy study confirmed the superiority of AFB over WLB in detecting premalignant lesions. AFB cannot be recommended as a general screening tool for lung cancer, but seems to be especially useful in patients with suspicious sputum cytology and normal chest X-ray, as well as in patients with a clinical suspicion of lung cancer."

Franz Stanzel:

Autofluorescence bronchoscopy in early detection of central premalignant and malignant bronchial changes


Conrad, Bachmann, Lehmann, Sack (Eds.):

Methods, possibilities and perspectives of pre-symptomatic tumor diagnostics

Pabst, Lengerich/Berlin, 348 pages, ISBN 3-89967-254-2

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(Pabst Publishers, June 20, 2009)


The information contained in these articles may or may not be in agreement with my own opinions. They are not being posted with the intention of being medical advice of any kind.

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