SBeth Posted November 16, 2004 Share Posted November 16, 2004 Can someone please tell me what the difference is (if any) between prophylactic cranial irradiation and whole brain radiation? Thank you Quote Link to comment Share on other sites More sharing options...
john Posted November 16, 2004 Share Posted November 16, 2004 PCI is WBR given before there is any evidence of a Brain met. They are the same though, I am not positive if the dose will be different for PCI vs WBR I read a total dosage of 30-36 Gy given in 2 Gy doses for PCI. I just read that typical dosage for WBR is 30 Gy in 10 fractions, so there may be a slight difference in PCI vs WBR. I guess with PCI there may be more fractions but total dosage is the same, probably to limit side effects - the total dosage is given in more fractions PCI is usually recommended only for limited SCLC that has responded to treatment. I read that a few oncs even recommended it for extensive that has a complete response. Also there are trials with NSCLC and PCI that are starting oncdoc can correct this is anything is incorrect. Quote Link to comment Share on other sites More sharing options...
kimblanchard Posted November 18, 2004 Share Posted November 18, 2004 What John said. Quote Link to comment Share on other sites More sharing options...
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