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NSCLC related to missing proteins?


Leslie221

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"Researchers at Vanderbilt University in Nashville found that type 2 receptors for Transforming Growth Factor-b -- a family of proteins that controls key functions such as cell growth and death -- were missing in non-small cell lung cancer victims."

"We've established for the first time that these important molecules are either missing or that their action is reduced in three-quarters of all cases of lung cancer," said lead researcher Professor Pran Datta.

"When we restored the molecules in lung cancer cells in mice, they reduced the ability of the cells to grow as tumors," he wrote in the British Journal of Cancer."

http://news.yahoo.com/s/nm/20051108/sc_nm/cancer_dc

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