Guest tmann11111 Posted September 19, 2007 Share Posted September 19, 2007 Anybody out there with BAC? If so, has any meds helped or slowed the growth down? My husband has tried Tarceva, Tarceva with Avastin, and 4 months of Carboplatin, Abraxane and Avastin. The doctor has run out of traditional therapies. My husband is close to entering a clinical trial with Velcade or Bortezomib. Anyone know anything about this drug regarding BAC? I guess that is why the trial, but does anyone know anything about Velcade? Thanks. Trudie Quote Link to comment Share on other sites More sharing options...
dadstimeon Posted September 19, 2007 Share Posted September 19, 2007 Hi Trudie, I have Stage IV/BAC going on month 64. It's one that is slow in developing and usually does not metastasize outside the lungs. So far I've had GEMZAR/CARPO, TAXOL, IRESSA (off the market but I think one can still get it, not poitive), NAVELBINE, TARCEVA and ALIMTA. Had great succes with all of them except gemzar/carpo. So don't kow why your doctor would not try one of these for your husband if he has not had them? Might want to inquire. Also if I started back up with treatments it would be Taxotere another one to ask about. Sorry can't help with Velcade. Let us know how things go, prayers for the best. Rich PS: Also answered your PM. Quote Link to comment Share on other sites More sharing options...
john Posted September 19, 2007 Share Posted September 19, 2007 There are a variety of EGFR inhibitors on trials HKI-272 lapatinib canertinib ZD6474 AEE788 CI-1033 EKB-569 ZD6474 (ZACTIMA™) Phase III Study in EGFR Failures Condition: Non-Small-Cell Lung Carcinoma dasantinib Quote Link to comment Share on other sites More sharing options...
DrWest Posted September 30, 2007 Share Posted September 30, 2007 I wrote a post at OncTalk about Velcade for lung cancer. It can't speak to what it might or might not do in his trial, but it might provide some useful background: http://onctalk.com/?p=769 I hope that helps. -Dr. West Quote Link to comment Share on other sites More sharing options...
weberle Posted January 8, 2008 Share Posted January 8, 2008 Hi I had success with Carboplatin, Taxol, and Avastin. I was on this regimine for 7 months and now am just on Avastin. I plateaued on Taceva which was tried first after 3 months. Sorry, not familiar with the others. Quote Link to comment Share on other sites More sharing options...
john Posted January 8, 2008 Share Posted January 8, 2008 There are other trials for BAC you might want to research. HKI-272 cetuximab (Erbitux) HKI-357 EKB-569 take care. Quote Link to comment Share on other sites More sharing options...
DawnB Posted January 18, 2008 Share Posted January 18, 2008 My Mom has had good results with Alimta and cisplatin plus radiation for her BAC. The only reason that she got this combo was because she was initially mis-diagnosed with adenocarcinoma, but we just found out today that the tumour has been reclassed as resectable, and she wouldn't have gotten there without the chemo/rads regimen that she was on. Quote Link to comment Share on other sites More sharing options...
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