flabet Posted October 29, 2003 Share Posted October 29, 2003 I'd really like to hear some success stories about Topotecan used as 2nd line chemo against SCLC. My husband has just been switched over from Carbo/VP-16, since that chemo was no longer working. What can anybody out there tell me about Topotecan. Thanks Flabet Quote Link to comment Share on other sites More sharing options...
Guest Jonathan Posted October 29, 2003 Share Posted October 29, 2003 Topotecan is a standard drug used against SCLC in the second line setting. If this fails in the future, as i am assuming he will have some good response to it, there are other drugs that can be considered. They are as follows... CPT-11 Taxol cytoxin with adriamycin and vincristine gemzar Jonathan Quote Link to comment Share on other sites More sharing options...
bart ziggie ( Greg ) Posted October 29, 2003 Share Posted October 29, 2003 Flabet, sorry to hear the carbo/vp-16 stopped working. Hopefully This Topotecan will do the job and shrink them tumors. I have done some looking around and from what i have seen this drug has had pretty good success at achieving responses. I too myself with my docs will be deciding by mon. morning what we will go with for my treatments. Thanks also Jonathan for posting the other meds i have looked at all of them and the cpt - 11 to me is pretty promising. I really dont know though. Well at any rate i wish your husband and you well flabet. Keep us posted. Greg Quote Link to comment Share on other sites More sharing options...
debbie412 Posted October 30, 2003 Share Posted October 30, 2003 my mom is currently on topotocan and the good news is the side effects are minimal. she had 8 rounds of cisplatin and cpt11, then etoposide, then adreamyecin and vincristine, and now topotocan. i am praying for a miracle. i will pray for your husband. Quote Link to comment Share on other sites More sharing options...
flabet Posted October 30, 2003 Author Share Posted October 30, 2003 Thanks to all of you. Jonathan, I truly appreciate your knowledgeable responses. You have so much good info for all of us. Greg, I am praying for you and Debbie, for your mom, also. Thanks again, and I will keep on praying for a miracle for all of us. Flabet Quote Link to comment Share on other sites More sharing options...
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