GBean Posted April 13 Share Posted April 13 Hello I am a caregiver of my husband, diagnosed with NSCLC in 2021 Stage 1B. He had an upper lobectomy and recovered beautifully in 2022. He had clear chest scans all year. This past January he ended up in ER due to seizure which later revealed stage IV brain metastisis of multiple lesions (no cancer present in his lungs, thankfully). After resection of one of the tumors, EGFR Exon 19 deletion was confirmed lung cancer mets to the brain. He has since had WBRT and has began Tagrisso in February. He also has to take Keppra for seizure management. His dosage of Tagrisso is 120mg currently and they want him to the max of 160mg for full penetration to the brain. Does anyone here have experience on Tagrisso at this dosage? The combination of the whole brain radiation, keppra and tagrisso is challenging with side effects. Curious to see how many there are at this higher dosage as most I research people are at the 80mg dosage. Thank you in advance and much health to everyone! Tom Galli 1 Quote Link to comment Share on other sites More sharing options...
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