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Jyoung20

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    Disappointed

    in MEMBER UPDATES

    Posted

    I am also on Tarceva alone and have had excellent results for 21 months now!! I pay a $45.00 co pay after the insurance. Genentech does have a program set up to help thsoe that can't get the medication..

    GOD BLESS AND PRAYERS!!

    Jamie

    Tumor Necrosis Therapy

    in LUNG CANCER IN THE NEWS

    Posted

    I thought this was very interesting

    Peregrine Pharmaceuticals' Tumor Necrosis Therapy Product for the Treatment of Lung Cancer Launched in China

    TUSTIN, Calif., Jan. 16 /PRNewswire-FirstCall/ -- Peregrine Pharmaceuticals, Inc. , a clinical stage biopharmaceutical company developing targeted therapeutics for the treatment of cancer and hepatitis C virus (HCV) infection, today reported that Shanghai Medipharm Biotech (Medipharm) has launched an iodine-131 radiolabeled Tumor Necrosis Therapy (TNT) antibody for the treatment of lung cancer in the People's Republic of China. The new drug is part of Peregrine's proprietary TNT technology platform that also includes its investigational drug Cotara®. Peregrine is currently conducting Phase II clinical trials of Cotara as a treatment for malignant brain cancer in the U.S. and India.

    According to clinical data reported by Medipharm in 2003, a registration study of advanced lung cancer patients in China demonstrated that Peregrine's radiolabeled TNT agent provided encouraging signs of patient benefit. Of the patients treated in the study, almost 4% experienced complete remissions, almost 31% had partial remissions involving at least 50% shrinkage of their tumors, 55% had their disease stabilized (representing no change in the tumor mass), and about 10% reported progressive disease. Responses to the therapy were defined according to the World Health Organization criteria for measuring solid tumors and confirmation of responses was obtained by using thoracic radiograph and computer tomography.

    "The market launch of this TNT anti-cancer agent in China is a signal event further validating the potential clinical utility of Peregrine's TNT technology," said Steven W. King, president and CEO of Peregrine. "This development is especially positive since lung cancer is a major and growing health issue in China. This launch is also timely since Peregrine has recently established a wholly owned subsidiary in China where we plan to pursue product development and commercialization activities on our own and in collaboration with Chinese biopharmaceutical partners."

    Peregrine had licensed certain rights to the company's TNT technology platform for development and commercialization in China exclusively to Cancer Therapeutics Laboratories, Inc. (CTL), which has a purported sublicense arrangement with Medipharm, the Chinese company developing and launching the new TNT drug for lung cancer.

    Peregrine recently announced that it had established a wholly foreign-owned enterprise (WFOE) in the People's Republic of China. The new subsidiary, Peregrine Beijing Pharmaceuticals Technology Development Ltd., is expected to engage in a variety of drug development and commercialization activities.

    Peregrine's proprietary Tumor Necrosis Therapy (TNT) approach links a radioactive isotope to a targeted monoclonal antibody that is designed to bind to a type of DNA that is exposed only on dead and dying cells. Solid tumors have a significant number of dead and dying cells at their center and the TNT agent's targeting mechanism enables it to home in on these dying tumor cells, delivering its radioactive "payload" directly to the center of the tumor mass. TNT agents thus literally destroy the tumor "from the inside out" with minimal radiation exposure to healthy tissue. Peregrine's TNT agent Cotara is currently in a multi-center trial in the U.S. for the treatment of glioblastoma multiforme (GBM) in collaboration with New Approaches to Brain Tumor Therapy (NABTT), a consortium of leading U.S. academic brain cancer centers. Peregrine has also received regulatory approval to initiate a Phase II Cotara trial for the treatment of GBM in India pending manufacturing clearance in that country. Cotara has been granted orphan drug status and fast track designation by the U.S. Food and Drug Administration for the treatment of GBM.

    does a port hurt

    in LC SURVIVORS

    Posted

    I did not feel alot of pain afterwards. I took Tylenol (OTC) and that was all I needed. The procedure was a little uncomfortable because I chose to use only local anesthesia.. Besides that, no problems... I will be praying for you!!!

    GOD BLESS!!

    Jamie

    P.S. It was one of the best choices I made!!!

    A thought from another thread...because I am the type to

    in GRIEF

    Posted

    Our individual timelines are a part of what we are, what we have gone through and what we continue to go through!! I understand Bill's concern about how it can be upsetting. But, it is what it is!! We have to face adversities every day of our lives and that will not change. Everyone is different and everyone will respond differently to treatment. Find your hope and stick with it no matter what you read..With that being said, I agree with the majority....keep the timelines.

    Bill,

    I am so sorry you are feeling the way that you do. You are a strong spirit, brilliant writer and obviously have a good outlook on life. Continue to hope and pray for the best even if statistics don't dictate a very positive outlook. When I was diagnosed, I was aware of my prognosis, the statistics, and the outcome but I will NEVER give up or let that get me down. I absolutely refuse to let it.. I live for today and hope for tomorrow. We all go through spells where we think of the future and if it will exist but I always try to remember that "Yesterday was the past, tommorrow is the future and today is a gift and that's why it is called the present" What a glorious present I have been given!!!! I pray that you continue to have many glorius present's!!

    GOD BLESS YOU MY FRIEND!!

    Jamie

    Please Think

    in GENERAL

    Posted

    I'm also curious to know which post you are referring to.....I truly feel that the people on this site that are posting all have viable reasons. Whether it be humor, venting, information,etc.(Except for the perverts that sometimes slip in the questionable sites after a one time sign-up) The last thing I would want is any one's feelings to be hurt. After all, we are here for support and we have all been hurt or are hurting in some way. Personally, this is my escape...It gives me an opportunity to speak what's on my mind without a negative confrontation or the fear of having one. Your post made me very uncomfortable and I am nt even sure if who you are talking. Believe me, I am not trying to upset anyone. I just believe that we need to keep in mind the purpose of a support group... SUPPORT..Unconditional Support!!!

    As earlier posts have stated, if there is something that anyone is in disagreement with then "take it with a grain of salt" and move on to what is pertinent information for you.

    WE ARE A FAMILY!!! WE ARE ALL IN THIS TOGETHER!!! Caregiver, Survivor, Supporter or Friend...This is our village and it has to continue to grow in order to make a difference. I pray that I haven't offended anyone as that was definately not my intention. But as a woman of faith, I do know that you are all my family unconditionally. If it's important to you, I can promise I will have complete empathy in what you have to say even if it doesn't apply to me. I know many times we search desperately for that magic bullet and we search in many different places. The source may be fabricated, the idea may be ridiculus, the treatment may not be credible but again we are desperate for a cure and not just for ourselves but also our family. Let me end by saying that I aplogize profusely if I offended anyone at anytime!!! I love you guys (all of you) and you are part of the reason I am still here!!!

    Thanks for listening!!

    GOD BLESS!!

    Jamie

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