JoniRobertWilson Posted June 27, 2004 Share Posted June 27, 2004 Are any of you suffering from both NSCLC and SCLC? Quote Link to comment Share on other sites More sharing options...
Donna G Posted June 27, 2004 Share Posted June 27, 2004 I am not suffering with bothe but I have heard of others cured on one and coming down with the other. It sounds really hard. So sorry. Donna G Quote Link to comment Share on other sites More sharing options...
jcawork Posted June 28, 2004 Share Posted June 28, 2004 How did this get diognosed? Why no chemo? Jen Quote Link to comment Share on other sites More sharing options...
JoniRobertWilson Posted June 28, 2004 Author Share Posted June 28, 2004 It was originally dx of sclc on 3/17 (limited) Chemo scheduled (3 sessions) and 28 days of radiation. Pleural effusion .... tacl procedure - went in with scopes, saw more cancer, new biopsy of NSCLC.... Quote Link to comment Share on other sites More sharing options...
Guest bean_si (Not Active) Posted June 28, 2004 Share Posted June 28, 2004 It appears I am in the same situation but the final conclusion has not been reached. It's difficult to deal with but I ain't giving up. My first biopsy said small cell. 2nd opinion at MD Anderson said ONLY non-small. Idiot onc says both based on the 2nd opinion his lab HAD to get when MD Anderson contradicted them. They better have enough tissue left to send to US Armed Services path lab for another opinion or I'll kick some bu**. You went to MDA, right? Given, their reputation, if they said small and non-small I would go with them. However, there are some very new sub-classifications, once classified as small cell. It could fall under Large Cell Neuoroendocrine Cancer LCNEC or the newest Large Cell Carcinoma with Neuroendocrine features LCC-NE I dunno but if they talked about neuroendocrine features, I would have a third opinion at Armed Services Path Lab. Thanks to John, I've discovered that the doctor working there, William Travis, developed the sub-classification on neuroendocrine non-small cancer. I figure they have to be able to differentiate. I'll keep you posted on any info I find on this. I'm scouring the web and devouring info. I know this is confusing. I hope I haven't confused you more. (I am confused myself for sure) You have my prayers. Cat Quote Link to comment Share on other sites More sharing options...
john Posted June 28, 2004 Share Posted June 28, 2004 There are also cases of mixed small and large cell. From what I have read, lung cancer sometimes will keep on mutating and may cause both small cell and large cell. One theory, why two chemotherapies work better than one is that the cancer will mutate as it is attacked by one chemo. In fact large may mutate to small and visa versa. By using two different kinds of chemo, this will attack the cancer in different ways so it can not survive via a mutation or other means (different signal pathways). http://www.mesothelioma-asbestosis.info ... ung-Cancer http://thorax.bmjjournals.com/cgi/content/full/53/6/450 It is definitely confusing. Quote Link to comment Share on other sites More sharing options...
berisa Posted June 29, 2004 Share Posted June 29, 2004 Your case is quite like my dad. The initial diagnosis is sclc. After the 1st cranitomy, they tested the cell and found NSCLC, but they tested again that concluded it should be sclc. It is not weird to find two types of cell I think. I don't have much knowledge on pathology, but you can check the info about the types & the subtypes of LC. Quote Link to comment Share on other sites More sharing options...
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