Jump to content

RET with high PD-L1


Recommended Posts


I was daignoses with RET mutation. High PD-L1.

Doctor put me on Keytruda. We will do scans in 8 weeks.  If the cancer stops growing or reduces in size I will continue on keytruda. 
If the treatment does not have a positive effect, doctor will add chemo to my treatment. 
Does anyone have an experience with Keytruda?positive results? Side effects?RET? 



Link to comment
Share on other sites

My first 4 treatments were Keytruda, Altimta & carboplatin. I have been on Keytruda & Alimta maintenance since June. I have had very few side effects but am not just on Keytruda so you will probably have fewer side effects if any. The tumor in my right lung had gotten smaller until my last scan when the size increased slightly. I have some bone and lymph node mets but it's not in any other major organ. I had SBRT radiation on the lung last month and am hoping for good results on my next scan. 

Link to comment
Share on other sites

  • 3 months later...

In case you haven't seen this, the FDA has just granted an accelerated approval to selpercatinib (LOXO-292; Retevmo) for the treatment of patients with RET alteration–positive non–small cell lung cancer (NSCLC). I had been watching the trials since it looked very promising.

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Reply to this topic...

×   Pasted as rich text.   Restore formatting

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

  • Create New...

Important Information

By using this site, you agree to our Terms of Use.