cherbut Posted May 8, 2004 Share Posted May 8, 2004 I am in the process of being accepted into a clinical trial to use Velcade, either alone or in conjuction with Taxotere. I just found out about this yesterday. I know it's being used to treat multiple myeloma. Does anyone out there have any information about any sucess rates using Velcade for nsclc or any information in general? Cherbut Diagnosed Sept. 2003 Stage IV nsclc Initial shrinkage with Carbo/Taxol Tumor started growing again per last 2 CAT scans Quote Link to comment Share on other sites More sharing options...
MO_Sugar Posted May 10, 2004 Share Posted May 10, 2004 Sorry sweetie, no info but you DO have my prayers! God bless, MO Quote Link to comment Share on other sites More sharing options...
Elaine Posted May 10, 2004 Share Posted May 10, 2004 Cherbut, All I really know is that I didn't fit the criteria for this trial. It sounded good to me--both medically and geographically. I will keep good thoughts headed your way. Keep us posted. Love Elaine Quote Link to comment Share on other sites More sharing options...
karen335 Posted May 11, 2004 Share Posted May 11, 2004 Cher, I haven't heard anything about this trial. Please keep us posted. Hope you get in and it works for you... Blessings and prayers, Karen Quote Link to comment Share on other sites More sharing options...
john Posted May 11, 2004 Share Posted May 11, 2004 Velcade is also called PS-341 or Bortezomib. If you do a search on PS-341 you can find older articles and more info on how effective it was, but since it is a trial drug, I don't think you will find much Make sure you ask if you at least get the standard treatment in both arms of the trial. The article below shows a case where a tumor in the chest wall completely disappeared. CAVEAT: This is only one patient. The article mentioned another patient that had a good response. You may need to register to medscape to see this article http://www.medscape.com/viewarticle/455616_10 DISCLOSURE: I used to own stock in Millennium (the manufacturer of Velcade) but I don't have any now. Quote Link to comment Share on other sites More sharing options...
Fay A. Posted May 11, 2004 Share Posted May 11, 2004 One of our members, Janet Kukawsky, was on the Velcade/Taxotere trial last year. She showed an initial response to the combo, but subsequently developed disease progression. Quote Link to comment Share on other sites More sharing options...
Surveyor Posted June 11, 2004 Share Posted June 11, 2004 Cher, Sorry I'm just making a reply. I'm new to the board. As you can see below, I've been through a phase I trail with Velcade. I had significant shrinkage in my tumors. The Velcade was administered on days 1, 4, 8 & 11. Carboplatin on day 1. Gemcitabine on days 1 & 8. Then, 10 days off and started again on 21 day cycle. CT's were given after every two cycles. There was no tumor shrinkage after cycle 4. I was a little nauseous the day following each intravenous injection of Velcade, but not real bad. Clinical trail was through U.C. Davis, California. Good luck! Quote Link to comment Share on other sites More sharing options...
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