Thanks for all your replies. My mom had her first round of camptosar and cisplatin yesterday. Hopefully she will tolerate it okay. I called and talked to the nurse who administers chemo at her doctor's office. My mom never told them about her extreme nausea. We're all scratching our heads about the nausea since she hadn't been getting chemo for awhile. Anyway, she does have Zofran, and the nurse said they give Emend and Aloxi there. I feel better that I did what I could to make them aware of my mom's circumstances. Addie, the fact that there are several of you here using Topotecan is what made me wonder if maybe she should use it too. I thought it might be a little easier on her. Anyway, I guess she'll try to stick with the cisplatin and camptosar for a while and see how it goes. Addie, I'm also keeping in the back of my head that your onc mentioned using Topotecan as a sort of maintenance drug, right? Thanks again. I don't know what I would do without you!