asmakis Posted September 6, 2006 Share Posted September 6, 2006 The doctor called my parents today to say that my dad does not qualify for the clinical trial of Eributux and Tarceva because it is only in phase 1 and it needs to be in phase 2 before my dad can have it. It won't be in phase 2 for another 6-9 months. So right now, my dad is on nothing and this is very hard for me to accept. He's been feeling pretty good, and he's still strong. I just feel like there has to be something out there. Please read my dad's profile below because I've added more details on chemo types and durations. My parents have an appointment with the oncologist tomorrow and I would like to have some things writen down for my parents to inquire about. Prior to this post, it was mentioned that he should have had a single agent chemo the second time around instead of a combination. This news bothers and I'm determined to get to the bottom of it. I'm asking for names of chemo's that others have been on or any advise or questions for my parents to ask tomorrow. I truly appreciate all your responses- it has really helped myself and my family. Amanda Quote Link to comment Share on other sites More sharing options...
KarenO Posted September 6, 2006 Share Posted September 6, 2006 What about Tarceva alone? Quote Link to comment Share on other sites More sharing options...
RandyW Posted September 6, 2006 Share Posted September 6, 2006 After Deb had tarceva single trstment for 6 months she went on to etoposide or VP-16. The day she passed she was to start Alimta/ Avastin combo. I know some her are Alimta Single agent I believe. Alimta Link; Click to be redirected: http://www.alimta.com/treatment/index.jsp?reqNavId=2 Docetaxel Link Single agent Chemo Link: http://www.jco.org/cgi/content/abstract/18/10/2095 Gemcitibine Versus Etoposide Link; http://www.jco.org/cgi/content/abstract/17/1/12 Quote Link to comment Share on other sites More sharing options...
Carleen Posted September 6, 2006 Share Posted September 6, 2006 I don't know too much about squamous cell NSCLC, but I did find this phase II trial that looks like your father would qualify for. http://www.clinicaltrials.gov/ct/show/NCT00365183?order=14 Quote Link to comment Share on other sites More sharing options...
Ry Posted September 7, 2006 Share Posted September 7, 2006 There are several other options for your dad. Ask about another treatment not in trial or maybe it is time for a second opinion. Quote Link to comment Share on other sites More sharing options...
Don Wood Posted September 7, 2006 Share Posted September 7, 2006 It doesn't seem like the field is exhausted already. Take a look at my wife's bio below and there may be something there you could suggest. My wife has metastatic nsclc, but adeno carcinoma. Don Quote Link to comment Share on other sites More sharing options...
Cheryl Ferguson Posted September 7, 2006 Share Posted September 7, 2006 I don't know where you reside but the Mary Crowley Research Cent @ Baylor Hospital in Dallas conducts many clinical trials. I have been on 3 seperate trials there and mayby there is one there for your Dad. Dr. Neil Senzer would be a good one to talk to. The number there is (214) 370-1870. Wishing you the best. Cheryl Quote Link to comment Share on other sites More sharing options...
john Posted September 13, 2006 Share Posted September 13, 2006 I have never heard of Tarceva being used on Squamous cell. I am not sure how well it would work. Erbitux is like tarveva. It targets EGFR but from the outside of the cell, not the inside. Actually there is new news out. June 6, 2006 http://www.nyba.org/news/member_news/jun062006_2.shtml Avastin (bevacizumab) is not recommended for squamous cell because of bleeding problems *maybe* photodynamic therapy is an option? http://jjco.oxfordjournals.org/cgi/content/full/29/1/45 Quote Link to comment Share on other sites More sharing options...
carlisle Posted October 3, 2006 Share Posted October 3, 2006 My brother had been taking Etopiside (Vepesid) but initially the doctors were talking about Tarceva. We never heard about it before. But Etoposide treatment was told to be the better one for his case. But before trying to change or alter any precription its better to make sure that there wont be any negative effects like bleeding or others. It differs from drugs to drugs. Quote Link to comment Share on other sites More sharing options...
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