Willw99 Posted June 7, 2007 Share Posted June 7, 2007 Message Willw99 Joined: 04 Jun 2007 Posts: 2 Location: Vancouver BC Posted: Thu Jun 07, 2007 8:54 am Post subject: need your input Diana and I saw the oncologist yesterday. She offered Di 4 options: 1. Do Nothing 2. Medication to relieve pain 3.A combination of carboplation and paclitaxel starting in August after she does 10 radiation treatments starting June 14th. 4.Participation in a clinical trial involving the above with experimental drug AZD2171 Does anyone have any experience with any of these options and the outcomes? I mentioned in my previous post that my darling wife for 36 yars has been diagnosed at stage 4 NSCLC with a tumor on the adrenal gland. I need your input to help her make a decision. Back to top Quote Link to comment Share on other sites More sharing options...
kamataca Posted June 8, 2007 Share Posted June 8, 2007 I'm so sorry, but I don't have any advice to offer. Our tx plan did not cover any of these options. Good luck to you in finding answers, and in making your decisions. Kelly Quote Link to comment Share on other sites More sharing options...
Adrian Posted June 8, 2007 Share Posted June 8, 2007 There are a lot of things I'd have to know first. Most importantly Id need to know a lot of details re: the clinical trial (what type of cancer fighting drug is it, what testing phase is it in? etc.) Other things being equal, I'd go Option 3! Im trying to figure out why Avastin isnt part of the option 3 regimen. I would certainly want that thrown into the mix if possible. fyi, my dad just finished 15 treatments of whole brain radiation and next week will begin a clinical trial where he will receive carboplatin/gemzar and avastin. Its a clinical trial because until recently they tended not to give avastin to people with brain mets due to the risk of brain bleeding. Quote Link to comment Share on other sites More sharing options...
Welthy Posted June 8, 2007 Share Posted June 8, 2007 Will, Carbo/Taxol is pretty standard first line treatment given to Stage IV patients. If they can radiate too, all the better. I'd go with radiation then the triplet you mentioned in the clinical trial including the AZD2171. I'd throw as much at it as possible. You need to be aggressive. What exactly are they radiating? It is a good sign that they feel they CAN radiate. Pain medicine can be given to help ease her pain at any time and shouldn't be contingent on treatment plans. Just my opinion, basically all of the above EXCEPT #1! Warm regards, Welthy Quote Link to comment Share on other sites More sharing options...
Surveyor Posted June 14, 2007 Share Posted June 14, 2007 Welthy is correct – you need to be aggressive. I would do # 3 or # 4. AZD2171 A substance that is being studied in the treatment of some types of cancer. It belongs to the families of drugs called angiogenesis inhibitors and vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors. Quote Link to comment Share on other sites More sharing options...
RandyW Posted June 14, 2007 Share Posted June 14, 2007 http://clinicaltrials.gov/ct/show/NCT00254943 http://www.drugs.com/clinical_trials/in ... -1149.html http://www.cancerpublications.com/newsl ... ticle4.htm this should give you a variety of info about This drug and its current trials and what it does. Quote Link to comment Share on other sites More sharing options...
rvillella Posted June 15, 2007 Share Posted June 15, 2007 I would try option 3 or 4. Pain management should be part of the program anyway. And if you don't like what you ONC is saying get a second opinion. The more informed you are the less you fear. Ralph Quote Link to comment Share on other sites More sharing options...
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