Hi, Melanie! Yep, your scenario is pretty normal. Lucie had a similar combination of chemo and it made her very sick, very tired. She got practically every side effect listed during the course of the chemo. BUT, it nailed that suckeroo! Loss of appetite is quite common,but you need to drink plenty of liquids and get proper nourishment nevertheless, so you can fight the beast. We found that meal snacks every two hours does better than three squares that you normally do. More apt to eat, and keeps something on the stomach to minimize nausea. Good lucik! Don