I think I hate Tarceva. Bill started taking 150 mg of Tarceva daily on July 2nd. At that time he seemed to be doing okay, albeit he was still loosing weight and seemed to be in a somewhat weaker state. He still wanted to get up every day, get a shower and run out on short errands.
For the past two weeks, he has changed. His appetite (and his weight) continue to diminish, he's never very motivated to do much and he says he just feels very sluggish. I know that much of this could be signs or symptoms of depression and we'll address those concerns with his oncologist on Tuesday.
This "so-called" rash from the Tarceva is awful and everyone is 100% correct when they say there is no good way to decribe it...there isn't and as a result of it he's become very self-conscious of his appearance and opts to stay home and secluded despite all of our friends and family who want to visit and spend time with him.
Okay...so that this post isn't all about my griping and whining about Tarceva...I really do have a question. I understand that a sudden increase in shortness of breath is a red flag and reason to contact the doctor; but has anyone experience severe...and I mean really severe hot/cold flashes with Tarceva. One minute we are driving with the air conditioning on in the car and he is sweating so bad his clothes become wet and two minutes later he wants the windows up, air off and actually tried to turn on the heat in the car...and it was over 90 degrees outside. Should we be concerned about this side effect and rush to spend a Friday night or the whole weekend in an urgent care or E.R. for a professional opinion; or do you think it can wait until our appointment on Tuesday? I just feel like many times we know more about the drugs and side effects than the physicians and nurses in E.R.s and don't want to spend our precious time there if we don't have to and quite frankly, I don't think I am prepared to hear that all of this could just be from the progression of the cancer. Aside from the fatigue, malise, rash and flashes...he's okay and wants to wait. What do you all think? And by the way, the hot/cold flashes are not constant, but happen 3-4 times a day when he is exerting himself.
Thanks for any help or advice.