Ed or Buddy Cutler Posted September 4, 2020 Share Posted September 4, 2020 I was diagnosed in July 2013 at age 67 with NSCLC-adenocarcinoma, with mets to my liver. At the time, there were only a few mutations that were known; my testing revealed that I had none of them (ALF, EGFR, KRAS negative). I was started on chemotherapy - carboplatin, Avastin, and Alimta. After 16 months, a new tumor was detected and I was declared chemo-resistant. At that time, there were no FDA-approved immunotherapy treatments, so I was shown several clinical trials to review and discuss with my oncologist. The trial that we selected was a phase 1 combination of MEDI4736 (now known as durvalumab or Imfinzi) and tremelimumab. Unfortunately (as there was significant reduction in tumor size), I was able to stay in that trial for only 7 months due to side effects. Within a few months, I was accepted into another trial (phase 1, oral drug code named PBF-509), which I have been in since January 2016 with no side effects other than fatigue, and stable since January 2017. Link to comment Share on other sites More sharing options...
Donna G Posted September 4, 2020 Share Posted September 4, 2020 Welcome Ed. You been in the battle for 7 years! You also show our crowd how many new treatments are becoming available ! The really good news is YOU ARE STABLE.. Thanks sharing your trip so far. Please keep us posted on how you are doing. Donna g Link to comment Share on other sites More sharing options...
GaryG Posted September 4, 2020 Share Posted September 4, 2020 Welcome, Wow what a story. Your tenacity and will are very inspiring. Welcome to the forum and thank you for sharing your story. Link to comment Share on other sites More sharing options...
Tom Galli Posted September 4, 2020 Share Posted September 4, 2020 Welcome Buddy, Your trial success is a remarkable story and provides hope for all of us with this horrid disease. Thanks for joining us. Stay the course. Tom Link to comment Share on other sites More sharing options...
BridgetO Posted September 5, 2020 Share Posted September 5, 2020 Hi Buddy and welcome! Yes, your story gives real inspiration to try clinical trials! keep us posted on how it's going. Bridget O Link to comment Share on other sites More sharing options...
Sabacat Posted September 5, 2020 Share Posted September 5, 2020 Welcome and thanks so much for sharing your story! Always great to hear about folks doing well as a result of clinical trials. Link to comment Share on other sites More sharing options...
LouT Posted September 6, 2020 Share Posted September 6, 2020 Ed, I'm glad you're here and thanks for sharing some of the incredible trials you were part of. It's good information to be able to impart to others who may not see the benefit of trials. Lou Link to comment Share on other sites More sharing options...
Lisa Haines Posted September 6, 2020 Share Posted September 6, 2020 Hi Ed, Welcome to the Forums! Great to have your here and I'm sure your input will be greatly appreciated ! Link to comment Share on other sites More sharing options...
catlady91 Posted September 8, 2020 Share Posted September 8, 2020 Fantastic Ed! Stories like yours give us hope! It's incredible how many different treatments are available now. Link to comment Share on other sites More sharing options...
LUNGevityKristin Posted September 8, 2020 Share Posted September 8, 2020 Hi, Ed! So glad you joined! Link to comment Share on other sites More sharing options...
Rower Michelle Posted September 9, 2020 Share Posted September 9, 2020 Hi Ed, Glad to meet you, but sorry to see you here. Thanks very much for volunteering for the clinical trials. Because of people like you I’m here today! Welcome. Michelle Link to comment Share on other sites More sharing options...
Recommended Posts
Archived
This topic is now archived and is closed to further replies.